Cucurbitacin D - 10mM in DMSO , CAS No.3877-86-9

CAS: 3877-86-9 Cat. No.: C656790 Formula: C₃₀H₄₄O₇ Molecular Weight: 516.67 EC Number: 686-158-7 PubChem CID: 5281318

GRADE & PURITY 10mM in DMSO

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Cucurbitacin D is an active component in Trichosanthes kirilowii , disrupts interactions between Hsp90 and two co-chaperones, Cdc37 and p23. Cucurbitacin D prevents Hsp90 client (Her2, Raf , Cdk6 , pAkt) maturation without induction of the heat shock response. Anti-cancer activity

IC50& Target:HSP90

Specifications

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Cucurbitacin D is an active component in Trichosanthes kirilowii , disrupts interactions between Hsp90 and two co-chaperones, Cdc37 and p23. Cucurbitacin D prevents Hsp90 client (Her2, Raf , Cdk6 , pAkt) maturation without induction of the heat shock resp

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

ACTIVATOR

Names and Identifiers

Isomeric SMILES

C[C@@]12C[C@H]([C@@H]([C@]1(CC(=O)[C@@]3([C@H]2CC=C4[C@H]3C[C@@H](C(=O)C4(C)C)O)C)C)[C@](C)(C(=O)/C=C/C(C)(C)O)O)O

Alternate CAS

3877-86-9

PubChem CID

5281318

NSC Number

308606

MeSH Entry Terms

23,24-dihydro-cucurbitacin D;cucurbitacin D;elatericin A

Molecular Weight

516.67