Cyclohexanone oxime - ≥97% , CAS No.100-64-1

CAS: 100-64-1 Cat. No.: C109682 Molecular Weight: 113.16 Beilstein Registry Number: 1616769 EC Number: 202-874-0
AVAILABLE TO ORDER
GRADE & PURITY ≥97%
Synonyms
2U60L00CGF | DTXCID701842 | NCGC00259692-01 | NSC 6300 | Cyclohexanone oxime, Vetec(TM) reagent grade, 97% | (HYDROXYIMINO)CYCLOHEXANE | AKOS000121564 | Cyclohexanone oxime | F1723-0300 | hydroxyiminocyclohexane | NCGC00091157-02 | CAS-100-64-1 | Cyclohex
Storage
Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
25g
C109682-25g
4
$13.90
100g
C109682-100g
5
$16.90
250g
C109682-250g
3
$26.90
500g
C109682-500g
3
$40.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 15 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
2U60L00CGF | DTXCID701842 | NCGC00259692-01 | NSC 6300 | Cyclohexanone oxime, Vetec(TM) reagent grade, 97% | (HYDROXYIMINO)CYCLOHEXANE | AKOS000121564 | Cyclohexanone oxime | F1723-0300 | hydroxyiminocyclohexane | NCGC00091157-02 | CAS-100-64-1 | Cyclohex
Specifications & Purity
≥97%
Storage
Room temperature
Shipped In
Normal
Purity
≥97%
Names and Identifiers
Pubchem Sid488180469
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180469
Canonical SmilesC1CCC(=NO)CC1
IUPAC NameN-cyclohexylidenehydroxylamine
InChIKeyVEZUQRBDRNJBJY-UHFFFAOYSA-N
INCHI1S/C6H11NO/c8-7-6-4-2-1-3-5-6/h8H,1-5H2
Isomeric SMILES C1CCC(=NO)CC1
WGK Germany 1
RTECS GW1925000
UN Number 2811
Packing Group I
Molecular Weight 113.16
Beilstein 1616769
Reaxy-Rn 1209600
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1209600&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic nitrogen compounds
ClassOrganonitrogen compounds
SubclassOximes
Intermediate Tree Nodes Not available
Direct ParentKetoximes
Alternative Parents Organopnictogen compounds  Organic oxygen compounds  Hydrocarbon derivatives  
Molecular FrameworkAliphatic homomonocyclic compounds
Substituents Ketoxime - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Aliphatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as ketoximes. These are organic compounds with the general formula RC(R')=NOH (R,R' = organyl).
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CASP1 Tchem Caspase-1 (6235 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lymphoblastoid cell (5959 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Liver microsomes (16955 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Liver (3974 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

17 results found

Lot NumberCertificate TypeDateItem
F2218231Certificate of AnalysisApr 02, 2026 C109682
F2218237Certificate of AnalysisApr 02, 2026 C109682
F2218241Certificate of AnalysisApr 02, 2026 C109682
F2218273Certificate of AnalysisApr 02, 2026 C109682
I2107277Certificate of AnalysisJun 09, 2025 C109682
I2107276Certificate of AnalysisJun 09, 2025 C109682
K2009184Certificate of AnalysisSep 05, 2024 C109682
K2009183Certificate of AnalysisSep 05, 2024 C109682
J2409253Certificate of AnalysisJul 27, 2024 C109682
J2409252Certificate of AnalysisJul 27, 2024 C109682
F2617101Certificate of AnalysisApr 30, 2024 C109682
G2415496Certificate of AnalysisApr 30, 2024 C109682
G2415495Certificate of AnalysisApr 30, 2024 C109682
B23061000Certificate of AnalysisFeb 10, 2023 C109682
F2218225Certificate of AnalysisJun 04, 2022 C109682
E1826035Certificate of AnalysisApr 11, 2022 C109682
E2422081Certificate of AnalysisMay 26, 2021 C109682

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Chemical and Physical Properties
SolubilitySoluble in water; Soluble in Ether,Alcohol
Flash Point(°F)217°F
Flash Point(°C)103°C
Boil Point(°C)210 °C
Melt Point(°C)90°C
Molecular Weight113.160 g/mol
XLogP31.200
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass113.084 Da
Monoisotopic Mass113.084 Da
Topological Polar Surface Area32.600 Ų
Heavy Atom Count8
Formal Charge0
Complexity90.700
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
1. Shiqin Sun, Yanshun Li, Ruixiang Sun, Luzhen Jiao, Shiwei Liu, Shitao Yu.  (2023)  Tailoring Zn-based diacidic functionalization of Deep eutectic solvent Catalyst: Green and efficient synthesis of ε-Caprolactam under mild conditions.  FUEL,      [PMID:] [10.1016/j.fuel.2023.129777]
2. Luzhi Zhang, Zenghe Liu, Lijie Sun, Lijuan Xiao, Qingbao Guan, Zhengwei You.  (2021)  Simple Solvent-Free Strategy for Synthesizing Covalent Adaptable Networks from Commodity Vinyl Monomers.  MACROMOLECULES,      [PMID:] [10.1021/acs.macromol.0c02766]
3. Yanyue Liu, Yisheng Sun, Mengting Ye, Liqin Zhu, Lili Zhang, Shuhua Zhu.  (2021)  Improvement in storage quality of postharvest tomato fruits by nitroxyl liposomes treatment.  FOOD CHEMISTRY,      [PMID:33951606] [10.1016/j.foodchem.2021.129933]
4. Shuangyu Wang, Jiaqi Liu, Peng Cheng, Zhihui Li, Dongsheng Zhang, Qiusheng Yang, Xinqiang Zhao, Yanji Wang.  (2021)  Application of an immobilized ionic liquid for the preparation of hydroxylamine via hydrolysis of cyclohexanone oxime.  ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE,  647  (7): (742-750).  [PMID:] [10.1002/zaac.202000370]
5. Chao Ge, Xiaofeng Li, Zhou Zhao, Zhifeng Yan, Dandan Lian, Jianjun Lu.  (2021)  Preparation of Silicalite-1 Nanosheets and its Application in Vapor-Phase Beckmann Rearrangement of Cyclohexanone Oxime.  INTEGRATED FERROELECTRICS,      [PMID:] [10.1080/10584587.2020.1728708]
6. Gan bing Yao, Zhan xiang Xia, Zhi hui Li, Chao Shao.  (2016)  Determination and modeling for solid–liquid phase equilibrium of ternary caprolactam + cyclohexanone oxime + methyl tert-butyl ether system.  FLUID PHASE EQUILIBRIA,      [PMID:] [10.1016/j.fluid.2016.03.002]
7. Jingjing Li, Tong Chen, Feng Deng, Jingyuan Wan, Yalan Tang, Pei Yuan, Liangke Zhang.  (2015)  Synthesis, characterization, and in vitro evaluation of curcumin-loaded albumin nanoparticles surface-functionalized with glycyrrhetinic acid.  International Journal of Nanomedicine,      [PMID:26346750] [10.2147/IJN.S88253]
8. Yi-Qiang Deng, Shuang-Feng Yin, Chak-Tong Au.  (2012)  Preparation of Nanosized Silicalite-1 and Its Application in Vapor-Phase Beckmann Rearrangement of Cyclohexanone Oxime.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,      [PMID:] [10.1021/ie3001277]
9. Yufen Wang, Yantao Wang, Yongqing Ma, Asma Mohmmad Elsharif, Chen Zhang, Weiran Yang, Christophe Len.  (2024)  A transition-metal-free catalytic reduction of benzylic alcohols and alkenes and N-formylation of nitroarenes mediated by iodide ions and formic acid.  NEW JOURNAL OF CHEMISTRY,      [PMID:] [10.1039/D4NJ03772C]
10. Kangjing Wu, Yuxi Lu, Shuai Wang, Xin Ma, Hong Zhong.  (2024)  Direct flotation recovery of malachite using a novel N-substituted hydroxamic acid: Adsorption mechanism and DFT calculation.  MINERALS ENGINEERING,      [PMID:] [10.1016/j.mineng.2024.109133]
11. Shiting Jia, Sai Geng, Mingming Han, Zhen Li, Bolin Zhao, Anyang Shi, Wenyu Xue, Jingyi Lao, Hailong Yu, Qiong Wu, Huihui Wang, Shiwei Liu.  (2025)  In-Site Boron Doping Microenvironmental Modulation toward Recyclable SAPO-11 for Efficient Beckmann Rearrangement of Cyclohexanone Oxime.  ACS Applied Materials & Interfaces,      [PMID:39946090] [10.1021/acsami.4c17070]
12. Shiqin Sun, Yanshun Li, Shiwei Liu.  (2025)  Task-specific deep eutectic solvents with synergistic catalytic performance as excellent and recyclable catalysts for Beckmann rearrangement.  RSC Advances,  15  (12): (8901-8912).  [PMID:40129632] [10.1039/D5RA01178G]
13. Huanyu Zeng, Cheng Xu, Xiaoping Wang, Jianhua Song, Dianzi Zhang, Benbin Li, Hongqin Hu, Dianhua Liu, Baowei Yu.  (2025)  Insights into active sites and structure performance relationships for Beckmann Rearrangement over nanosphere sulfonic acid resins.  Molecular Catalysis,      [PMID:] [10.1016/j.mcat.2025.115144]
14. You Xu, Huizhen Wang, Jiabing Geng, Yufeng Yuan, Kai Deng, Hongjie Yu, Ziqiang Wang, Hongjing Wang, Liang Wang.  (2026)  Asymmetric p-d-p Orbital Hybridization and Atomically Ordered Configuration in Intermetallic PdInBi Metallene Induced Short-Path Hydrogen Spillover for Electrosynthesis of Oximes.  APPLIED CATALYSIS B-ENVIRONMENTAL,      [PMID:] [10.1016/j.apcatb.2026.126381]
15. Fuhua Zhang, Yuxin Zhang, Pengpeng Wen, Yuhao Nie, Yanyuan Song, Qing Zhu, Wenbo Gong, Yufei Liu, Jingyi Lao, Jialuo Yin, Huihui Wang, Yue Liu, Sai Geng, Shiwei Liu.  (2026)  Dynamic Brønsted–Lewis coordination switching enables self-repairing Beckmann catalysis.  JOURNAL OF CATALYSIS,      [PMID:] [10.1016/j.jcat.2026.116827]
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