DCOIT - Moligand™, 10 mM in DMSO , CAS No.64359-81-5

CAS: 64359-81-5 Cat. No.: D1500728 Molecular Weight: 282.22 EC Number: 264-843-8
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1ml
D1500728-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$28.90
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

DCOIT is a representative isothiazolinone that stimulates the gonadotropin-releasing hormone receptor ( GnRHR )-mediated synthesis of follicle-stimulating hormone and luteinizing hormone in the brain. DCOIT interferes with G protein-coupled receptors, MAPK and Ca 2+ signaling cascades.

Specifications

Specifications & Purity
Moligand™, 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
AGONIST
Names and Identifiers
Isomeric SMILES CCCCCCCCN1C(=O)C(=C(S1)Cl)Cl
RTECS NX8157075
Molecular Weight 282.22
Reaxy-Rn 1110842
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1110842&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Melt Point(°C)42 °C
Documents & Articles
Citations of This Product
References
1. Fengqin Li, Yang Zhou, Yuxue Hu, Xiaoming Feng, Guizhong Tian.  (2025)  Study on synergistic antifouling of super slippery drug-loaded modified film based on electrospinning-electrospray in situ process.  Surfaces and Interfaces,      [PMID:] [10.1016/j.surfin.2025.107196]
2. Tongtong Ding, Luyao Xu, Xiangting Liu, Liang Ma, Yingxin Cui, Dalong Li, Xiuhua Sun, Changlu Gao.  (2022)  A Cu2O-based marine antifouling coating with controlled release of copper ion mediated by amphiphilic PLMA-b-PDMAEMA copolymers.  PROGRESS IN ORGANIC COATINGS,      [PMID:] [10.1016/j.porgcoat.2022.107003]
3. Abid Ali, Lina Song, Jiankun Hu, Jingxian Jiang, Qingqing Rao, Muhammad Shoaib, Shah Fahad, Yongjie Cai, Xiaoli Zhan, Fengqiu Chen, Qinghua Zhang.  (2020)  Synthesis and characterization of caprolactone based polyurethane with degradable and antifouling performance.  CHINESE JOURNAL OF CHEMICAL ENGINEERING,      [PMID:] [10.1016/j.cjche.2020.11.007]
4. Qiao Sen, Cao Hongjie, Yang Yue, Jin Ruofei, Zhou Jiti.  (2020)  Preparation and antifouling performance of PVDF-DCOIT composite hollow fiber membranes.  KOREAN JOURNAL OF CHEMICAL ENGINEERING,  37  (3): (497-504).  [PMID:] [10.1007/s11814-019-0436-2]
5. Peng-Yu Zhu, Tian-Xiao Liang, Muhammad Arslan Hafeez, Muhammad Yasir, Dan-Qing Feng, Chun-Feng Ma, Cheng Zhang, Lin Liu.  (2024)  A novel strategy for design of mechanically robust antifouling coatings via bifunctional domain engineering.  Materials Today Chemistry,      [PMID:] [10.1016/j.mtchem.2024.102207]
6. Shuqing Wei, Guangling He, Yuhao Yue, Qianju Liu, Xinhao Liu, Liangmin Yu, Lei Dong.  (2025)  Construction and properties of hydrogel microlayer on the surface of water-based self-polishing antifouling resin coating.  PROGRESS IN ORGANIC COATINGS,      [PMID:] [10.1016/j.porgcoat.2025.109259]
7. Jiayin Li, Guangmeng Chen, Shuaipeng Wang, Jinyue Dai, Shuan Liu, Guangming Lu, Weiwei Zhao, Xiaoqing Liu.  (2025)  Sea-water degradable self-polishing epoxy thermosets for antifouling coatings.  PROGRESS IN ORGANIC COATINGS,      [PMID:] [10.1016/j.porgcoat.2025.109162]
8. Junqiao Zhou, Jiayin Li, Cong Cheng, YuJuan Yao, Yu Li, Hao Liu, Laiyan Wu.  (2024)  Unraveling the binding behavior of the antifouling biocide 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one with human serum albumin: Multi-spectroscopic, atomic force microscope, computational simulation, and esterase activity.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:38906347] [10.1016/j.ijbiomac.2024.133266]
Solution Calculators
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