Dexamethasone Solution (10mM) - BioReagent, for Cell culture, Sterile, 10 mM in DMSO , CAS No.50-02-2

CAS: 50-02-2 Cat. No.: C1524668 Formula: C₂₂H₂₉FO₅ Molecular Weight: 392.46 Beilstein Registry Number: 2066651 EC Number: 200-003-9

GRADE & PURITY BioReagent, for Cell culture, Sterile, 10 mM in DMSO

Synonyms

Dexamethasone Solution | DEX | DXM

Storage

Store at 2-8°C,Do not freeze

Shipped In

Wet ice

Overview

Dexamethasone is an adrenocortical hormone substance with multiple pharmacological effects including anti‑inflammatory, anti‑allergic, immunosuppressive and anti‑shock activities. It exerts certain physiological effects on cell culture, cell signal transduction and gene expression. Dexamethasone can induce disorder of hepatic glucose and lipid metabolism; inhibit the activation of the PI3K/Akt pathway and trigger osteoblast apoptosis; elevate intracellular ROS levels and mitochondrial superoxide production. It also induces the differentiation of human mesenchymal stem cells (MSCs), triggers autophagy in B‑cell acute lymphoblastic leukemia (B‑ALL), down‑regulates activated NF‑κB levels in immature dendritic cells (DCs), and suppresses their differentiation into mature DCs.

Dexamethasone Solution is a cell‑culture‑grade 10 mM stock solution. Researchers may dilute it at an appropriate ratio according to experimental requirements prior to direct use.

Product Properties:

CAS NO.: 50‑02‑2

Formula: C₂₂H₂₉FO₅

Molecular weight: 392.461

Appearance: Colorless transparent solution

Solubility: Soluble in ethanol and DMSO, slightly soluble in water

Melting point: 255～264 °C

Structure:

Precautions:

1. For your safety and health, please wear a lab coat and disposable gloves during operation.

2. This reagent is for research use only.

Specifications

Synonyms

Dexamethasone Solution | DEX | DXM

Specifications & Purity

BioReagent, for Cell culture, Sterile, 10 mM in DMSO

Stability And Storage

Store at 2-8°C long term (24 months). Store in the dark.

Storage

Store at 2-8°C,Do not freeze

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

BioReagent, for Cell culture, Sterile

Product Line

Biological Products

Product Properties

ALogP

1.9

Names and Identifiers

Isomeric SMILES

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C

WGK Germany

2

RTECS

TU3980000

Alternate CAS

23495-06-9,50-02-2

NSC Number

34521

MeSH Entry Terms

Decaject;Decaject L.A.;Decaject-L.A.;Decameth;Decaspray;Dexamethasone;Dexasone;Dexpak;Hexadecadrol;Hexadrol;Maxidex;Methylfluorprednisolone;Millicorten;Oradexon

Molecular Weight

392.46

Beilstein

2066651

Reaxy-Rn

2341697

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2341697&ln=

Chemical and Physical Properties

• Solubility: Soluble in ethanol and DMSO, slightly soluble in water
• Melt Point(°C): 262-264°C