Dicyanocobinamide - Moligand™, ≥93% , CAS No.27792-36-5

CAS: 27792-36-5 Cat. No.: D463289 Formula: C₅₀H₇₂CoN₁₃O₈ Molecular Weight: 1042.12 EC Number: 687-104-5 PubChem CID: 6450878

GRADE & PURITY Moligand™, ≥93%

Synonyms

Factor B | Cobinamide dicyanide | Etiocobalamin

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Dicyanocobinamide, also known as factor b is a coenzyme B12 precursor. It has a corrin ring structure with four of the six coordination sites of the cobalt (Co) atom being the pyrrole nitrogen atoms.Dicyanocobinamide has been used for the crystallization of vitamin B12-binding protein (BtuF). It has also been used for the destabilization of BtuCD-BtuF Interaction.For use in determining non-intrinsic factor (R protein) in intrinsic factor preparations.

Specifications

Synonyms

Factor B | Cobinamide dicyanide | Etiocobalamin

Specifications & Purity

Moligand™, ≥93%

Biochemical and Physiological Mechanisms

Dicyanocobinamide (Cbi) functions as a soluble guanylate cyclase (sGC) co-activator and targets the N-terminal regulatory regions. This action is similar to the effect of forskolin on adenylyl cyclases. Dicyanocobinamide elevates the intracellular cyclic

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Purity

≥93%

Names and Identifiers

• Pubchem Sid: 504764208
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504764208
• Canonical Smiles: CC1=C2C(C(C([N-]2)C3(C(C(C(=N3)C(=C4C(C(C(=N4)C=C5C(C(C1=N5)CCC(=O)N)(C)C)CCC(=O)N)(C)CC(=O)N)C)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)(C)CCC(=O)NCC(C)O.[C-]#N.[C-]#N.[Co]
• IUPAC Name: cobalt;3-[(1R,2S,3S,5Z,7S,8S,10Z,13S,15Z,17R,18R)-2,7,18-tris(2-amino-2-oxoethyl)-3,13-bis(3-amino-3-oxopropyl)-17-[3-(2-hydroxypropylamino)-3-oxopropyl]-1,2,5,7,12,12,15,17-octamethyl-8,13,18,19-tetrahydro-3H-corrin-24-id-8-yl]propanamide;dicyanide
• InChIKey: NWXVHVXSDZHCFS-TWXWJCICSA-M
• INCHI: 1S/C48H73N11O8.2CN.Co/c1-23(60)22-55-38(67)16-17-45(6)29(18-35(52)64)43-48(9)47(8,21-37(54)66)28(12-15-34(51)63)40(59-48)25(3)42-46(7,20-36(53)65)26(10-13-32(49)61)30(56-42)19-31-44(4,5)27(11-14-33(50)62)39(57-31)24(2)41(45)58-43;2*1-2;/h19,23,26-29,43,60H,10-18,20-22H2,1-9H3,(H14,49,50,51,52,53,54,55,56,57,58,59,61,62,63,64,65,66,67);;;/q;2*-1;/p-1/t23?,26-,27-,28-,29+,43?,45-,46+,47+,48+;;;/m1.../s1
• Isomeric SMILES: C/C/1=C/2\[C@@]([C@@H](C(=N2)/C=C\3/C([C@@H](C(=N3)/C(=C\4/[C@]([C@H](C([N-]4)[C@]5([C@@]([C@@H](C1=N5)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)(C)CCC(=O)NCC(C)O)/C)CCC(=O)N)(C)C)CCC(=O)N)(C)CC(=O)N.[C-]#N.[C-]#N.[Co]
• PubChem CID: 6450878
• Molecular Weight: 1042.12

Chemical and Physical Properties

• Flash Point(°F): Not applicable
• Flash Point(°C): Not applicable