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Diphtheria Toxin(CRM197), CAS No.MFCD00163490
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GRADE & PURITY ≥95%
Expression system
E. coli
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Why this grade
≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
The diphtheria toxin of Corynebacterium diphtheriae has been used in: microglia depletion, study of post-traumatic stress disorder in mice; Intraperitoneally injected in transgenic mice to select hybrids after fusion of transplanted hematopoietic stem cells and progenitor cells (HSPCs) during ablation; To study the effect on eosinophilic lineal transformed progenitor cells in eosinophilic deficient mouse strain (iPHIL).
Diphtheria toxin can be used as a toxin element in the construction of cell-specific cytotoxic immunotoxins. Bacterial toxin translocation domains with natural endosome escape mechanisms have been used to develop effective non-viral vectors for gene therapy.
Specifications
Product Name
Diphtheria Toxin(CRM197), CAS No.MFCD00163490
Synonyms
CRM197
Specifications & Purity
≥95%
Sequence
MGADDVVDSS KSFVMENFSS YHGTKPGYVD SIQKGIQKPK SGTQGNYDDD WKEFYSTDNK HDAAGYSVDN ENPLSGKAGG VVKVTYPGLT KVLALKVDNA ETIKKELGLS LTEPLMEQVG TEEFIKRFGD GASRVVLSLP FAEGSSSVEY INNWEQAKAL SVELEINFET RGKRGQDAKY EYMAQACAGN RVRRSVGSSL SCINLDWDVI RDKTKTKIES LKEHGPIKNK MSESPNKTVS EEKAKQYLEE FHQTALEHPE LSELKTVTGT NPVFAGANYA AWAVNVAQVI DSETADNLEK TTAALSILPG IGSVMGIADG AVHHNTEEIV AQSIALSSLM VAQAIPLVGE LVDIGFAAYN FVESIINLFQ VVHNSYNRPA YSPGHKTQPF LHHHHHH
CAS
MFCD00163490
Molecule Type
Protein
Storage and Shipping
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
<<<<<<< HEAD Download SDS → ======= Download SDS → >>>>>>> release248-p3✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
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Certificates (CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 H2627017 | Certificate of Analysis | Sep 04, 2026 | D684675 |
| F2622291 | Certificate of Analysis | Jun 10, 2026 | D684675 |
| D2614350 | Certificate of Analysis | Apr 03, 2026 | D684675 |
| I2504266 | Certificate of Analysis | Sep 01, 2025 | D684675 |
| D2524090 | Certificate of Analysis | Mar 12, 2025 | D684675 |
| A2507321 | Certificate of Analysis | Jan 03, 2025 | D684675 |
| J2428320 | Certificate of Analysis | Oct 23, 2024 | D684675 |
| I2418465 | Certificate of Analysis | Sep 12, 2024 | D684675 |
| I2418466 | Certificate of Analysis | Sep 12, 2024 | D684675 |
| F2417253 | Certificate of Analysis | Jun 12, 2024 | D684675 |
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