Ditolylguanidine - Moligand™, 10 mM in DMSO , CAS No.97-39-2

CAS: 97-39-2 Cat. No.: D1496951 Formula: C₁₅H₁₇N₃ Molecular Weight: 239.32 Beilstein Registry Number: 12803 EC Number: 202-577-6

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Ditolylguanidine (1,3-Di-o-tolylguanidine) is an agonist of sigma receptor ( σ1/σ2 receptor ) with K i values of 69 and 21 nM for σ1 and σ2 receptors, respectively. Ditolylguanidine effectively inhibits the growth of small cell lung cancer cells. Ditolylguanidine can be used for the research of lung cancer .

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

AGONIST

Names and Identifiers

• Isomeric SMILES: CC1=CC=CC=C1NC(=NC2=CC=CC=C2C)N
• WGK Germany: 3
• RTECS: MF1400000
• Alternate CAS: 97-39-2,41130-39-6 (hydrochloride)
• NSC Number: 473
• MeSH Entry Terms: 1,3-di-(2-tolyl)guanidine;1,3-di-o-tolylguanidine;1,3-di-ortho-tolyl-guanidine;1,3-ditolylguanidine;1,3-ditolylguanidine hydrochloride;N,N'-bis(2-methylphenyl)guanidine
• Molecular Weight: 239.32
• Beilstein: 12803
• Reaxy-Rn: 6768818
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6768818&ln=

Chemical and Physical Properties

• Melt Point(°C): 175 °C

References

1. Ye Gao, Teng Zhang, Changyou Yu, Peiyi Li, Ningning Tian, Songgu Wu.  (2020)  The effect of solvents on solid-liquid phase equilibrium of 1,3-Di-o-tolylguanidine.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2020.113147]

2. Wei Guo, Hui He, Hongxiang Zhu, Xudong Hou, Xingjuan Chen, Shile Zhou, Shuangfei Wang, Lingtao Huang, Jiehan Lin.  (2019)  Preparation and properties of a biomass cellulose-based colorimetric sensor for Ag+ and Cu2+.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2019.05.044]

3. Yuan Zhang, Dong Wang, Gaili Liu, Kun Wang, Shaomin Shuang, Chuan Dong.  (2025)  A novel CuO nanoparticle loaded DMSN@MnO2 nanozyme as an optical platform for 2-mercaptobenzothiazole assays and biotoxicity mitigation.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.159363]

4. Zi-Lin He, Jun-Hua Wei, Jian-Bin Luo, Zhi-Zhong Zhang, Jing-Hua Chen, Xiu-Xian Guo, Dai-Bin Kuang.  (2024)  Guanidinium-Based Manganese(II) Bromide with High Glass-Forming Ability for Thermoplastic Curved X-ray Imaging.  Laser & Photonics Reviews,      [PMID:] [10.1002/lpor.202301249]

Frequently Asked Questions

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 97-39-2, the molecular formula is C15H17N3, and the molecular weight is 239.32 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.