DL-Menthol - analytical standard, Moligand™ , Activator of TRPA1;Gating inhibitor of TRPA1;Activator of TRPM8;Activator of TRPV3, CAS No.89-78-1, Activator of TRPA1;Gating inhibitor of TRPA1;Activator of TRPM8;Activator of TRPV3
DL-Menthol - analytical standard, Moligand™ , Activator of TRPA1;Gating inhibitor of TRPA1;Activator of TRPM8;Activator of TRPV3, CAS No.89-78-1, Activator of TRPA1;Gating inhibitor of TRPA1;Activator of TRPM8;Activator of TRPV3
GRADE & PURITYAnalytical standard?Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.Moligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
analytical standard, Moligand™ Analytical standard,Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Room temperature Ships Normal Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 24 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
DL-Menthol triggers cold-sensitive TRPM8 receptors in the skin neurons in vitro. The (-)-Menthol form exists naturally in nature, primarily found in fruit extracts or spearmint extracts. This racemic mixture could theoretically be created by the hydrogenation of the monoterpene pulegone. A chemical which triggers cold-sensitive TRPM8 receptors in the skin neurons in vitro.
This compound belongs to the class of organic compounds known as menthane monoterpenoids. These are monoterpenoids with a structure based on the o-, m-, or p-menthane backbone. P-menthane consists of the cyclohexane ring with a methyl group and a (2-methyl)-propyl group at the 1 and 4 ring position, respectively. The o- and m- menthanes are much rarer, and presumably arise by alkyl migration of p-menthanes.
External Descriptors
a monoterpenol
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
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