DL-Threonine - BioReagent, for cell culture, suitable for insect cell culture , CAS No.80-68-2

CAS: 80-68-2 Cat. No.: D434240 Formula: C₄H₉NO₃ Molecular Weight: 119.12 EC Number: 201-300-6

GRADE & PURITY BioReagent, for Cell culture, Suitable for insect cell culture

Synonyms

DL-allo-Threonine | DL-Threonine (contains DL-Allothreonine) | 760PJT2SS0 | CHEBI:38263 | DL-2-Amino-3-hydroxybutanoic acid | H-DL-Thr-OH | 2-amino-3-hydroxybutanoic acid | 2-amino-3-hydroxy-butanoic acid | H-DL-allo-Thr-OH | (±)-2-Amino-3-hydroxybutyric

Storage

Room temperature

Overview

General Description

L-Threonine is an essential proteinogenic amino acid incorporated into proteins as directed by the genetic code. Threonine is a polar amino acid with a hydroxyl containing R-group that can participate in glycosylation reactions.

Application

For use in insect and mammalian cell culture applications where the pure L-form is not required.Suitability': 'This DL-Threonine has been qualified for use in animal and insect cell culture applications.

Specifications

Synonyms

DL-allo-Threonine | DL-Threonine (contains DL-Allothreonine) | 760PJT2SS0 | CHEBI:38263 | DL-2-Amino-3-hydroxybutanoic acid | H-DL-Thr-OH | 2-amino-3-hydroxybutanoic acid | 2-amino-3-hydroxy-butanoic acid | H-DL-allo-Thr-OH | (±)-2-Amino-3-hydroxybutyric

Specifications & Purity

BioReagent, for cell culture, suitable for insect cell culture

Storage

Room temperature

Grade

BioReagent, for Cell culture, Suitable for insect cell culture

Names and Identifiers

Pubchem Sid

528764184

Canonical Smiles

C[C@H](O)[C@@H](N)C(O)=O

IUPAC Name

2-amino-3-hydroxybutanoic acid

InChIKey

AYFVYJQAPQTCCC-UHFFFAOYSA-N

INCHI

1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)

Isomeric SMILES

CC(C(C(=O)O)N)O

Molecular Weight

119.12

Reaxy-Rn

1721643

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1721643&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Alpha amino acids
• Alternative Parents: Short-chain hydroxy acids and derivatives Beta hydroxy acids and derivatives Fatty acids and conjugates Secondary alcohols Amino acids Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha-amino acid - Beta-hydroxy acid - Short-chain hydroxy acid - Hydroxy acid - Fatty acid - Amino acid - Secondary alcohol - Carboxylic acid - Monocarboxylic acid or derivatives - Alcohol - Primary amine - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Primary aliphatic amine - Organic oxide - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Amine - Organic nitrogen compound - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon).
• External Descriptors: alpha-amino acid

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Melt Point(°C): 230°C(dec.)(lit.)
• Molecular Weight: 119.120 g/mol
• XLogP3: -2.900
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 119.058 Da
• Monoisotopic Mass: 119.058 Da
• Topological Polar Surface Area: 83.600 Ų
• Heavy Atom Count: 8
• Formal Charge: 0
• Complexity: 93.300
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 2
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1