GRADE & PURITYMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.10mM in DMSO
Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
DUB-IN-1 is an active inhibitor of ubiquitin-specific proteases (USPs) , with an IC 50 of 0.85 μM for USP8
In Vitro
DUBs-IN-1 (22 d) is an active inhibitor of ubiquitin-specific proteases, with an IC 50 of 0.85 μM for USP8. DUBs-IN-1 is inactive toward USP7 (IC 50 , >100 μM). DUBs-IN-1 and its analogs reduce the viability of HCT116 colon and PC-3 prostate cancer cell lines with IC 50 s ranging from 0.5 μM to 1.5 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:IC50: 0.24 μM (USP8)
Specifications
Specifications & Purity
Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms
DUB-IN-1 is an active inhibitor of ubiquitin-specific proteases (USPs) , with an IC 50 of 0.85 μM for USP8.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
INHIBITOR
Names and Identifiers
Molecular Weight
337.33
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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