Dyphylline - Moligand™, 10mM in DMSO , Phosphodiesterase 4 inhibitor, CAS No.479-18-5, Phosphodiesterase 4 inhibitor

CAS: 479-18-5 Cat. No.: D408406 Formula: C₁₀H₁₄N₄O₄ Molecular Weight: 254.24 Beilstein Registry Number: 284563 EC Number: 207-526-1

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

Diprophylline | 7-(2,3-dihydroxypropyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

Dyphylline Dyphylline (Diprophylline) is a xanthine derivative with bronchodilator and vasodilator effects.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonyms

Diprophylline | 7-(2,3-dihydroxypropyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione

Specifications & Purity

Moligand™, 10mM in DMSO

Biochemical and Physiological Mechanisms

Dyphylline (Diprophylline) is a xanthine derivative with bronchodilator and vasodilator effects.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Mechanism of action

Phosphodiesterase 4 inhibitor

Product Properties

• ALogP: -1.8

Names and Identifiers

• Isomeric SMILES: CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(CO)O
• WGK Germany: 3
• RTECS: XH5100000
• Molecular Weight: 254.24
• Beilstein: 284563
• Reaxy-Rn: 284563
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=284563&ln=

Chemical and Physical Properties

• Solubility: Solubility (25°C) In vitro Water: 100 mg/mL DMSO: Insoluble; Ethanol: Insoluble
• Melt Point(°C): 160-165°C

References

1. Li-Li He, Pei Song, Ai-Jun Wang, Jie-Ning Zheng, Li-Ping Mei, Jiu-Ju Feng.  (2015)  A general strategy for the facile synthesis of AuM (M = Pt/Pd) alloyed flowerlike-assembly nanochains for enhanced oxygen reduction reaction.  Journal of Materials Chemistry A,  3  (10): (5352-5359).  [PMID:] [10.1039/C4TA06627H]

2. Wei Yin, Huihui Chai, Renhua Liu, Changhu Chu, John A. Palasota, Xiaohui Cai.  (2014)  Click N-benzyl iminodiacetic acid: Novel silica-based tridentate zwitterionic stationary phase for hydrophilic interaction liquid chromatography.  TALANTA,      [PMID:25476290] [10.1016/j.talanta.2014.08.077]

3. Wang Rui-qiang, Yin Yu-jing, Li Hua, Wang Yi, Pu Juan-Juan, Wang Rui, Dou Huan-jing, Song Chuan-jun, Wang Rui-yong.  (2012)  Comparative study of the interactions between ovalbumin and three alkaloids by spectrofluorimetry.  MOLECULAR BIOLOGY REPORTS,  40  (4): (3409-3418).  [PMID:23266670] [10.1007/s11033-012-2418-x]

Frequently Asked Questions

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 479-18-5, the molecular formula is C10H14N4O4, and the molecular weight is 254.24 g/mol.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.