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Endothelin 1，TFA, CAS No.117399-94-7(free)
AVAILABLE TO ORDER
GRADE & PURITY ≥95%
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Why this grade
≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Product Introduction
Soluble in water.
A 21-amino acid polypeptide with potent vasoconstrictive action. Produces convulsions, arterial hypertension, and metabolic activation of periventricular white and gray matter. Its effects are mediated via L-type Ca2+ channels. Reported to activate phospholipase C in fibroblasts expressing ETA receptors.
Biochemical mechanism
Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
Potent vasoconstrictive action
Specifications
Product Name
Endothelin 1，TFA, CAS No.117399-94-7(free)
Synonyms
ET-1, CSCSSLMDKECVYFCHLDIIW
Specifications & Purity
≥95%
Sequence
Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridge: Cys1-Cys15, Cys3-Cys11)
CAS
117399-94-7(free)
Molecule Type
Peptide
Storage and Shipping
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 B2223653 | Certificate of Analysis | Dec 10, 2025 | E359015 |
| B2223654 | Certificate of Analysis | Dec 10, 2025 | E359015 |
| B2223655 | Certificate of Analysis | Dec 10, 2025 | E359015 |
| B2223662 | Certificate of Analysis | Dec 10, 2025 | E359015 |
| B2223663 | Certificate of Analysis | Dec 10, 2025 | E359015 |
| B2223664 | Certificate of Analysis | Dec 10, 2025 | E359015 |
| G2502090 | Certificate of Analysis | Feb 10, 2022 | E359015 |
Citations of This Product
References
| 1. Nashwa Amin, Shijia Chen, Qiannan Ren, Xiaoning Tan, Benson O. A. Botchway, Zhiying Hu, Fengpei Chen, Shan Ye, Xiaoxue Du, Zuobing Chen, Marong Fang. (2021) Hypoxia Inducible Factor-1α Attenuates Ischemic Brain Damage by Modulating Inflammatory Response and Glial Activity. Cells, 10 (6): (1359). [PMID:34205911] [10.3390/cells10061359] |
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Frequently Asked Questions
What is the purity of this product?
This product is supplied at ≥95% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 117399-94-7(free).
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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