Ethylene glycol monophenyl ether - ≥98% , CAS No.122-99-6

CAS: 122-99-6 Cat. No.: E109367 Molecular Weight: 138.16 Beilstein Registry Number: 1364011 EC Number: 204-589-7
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
DTXSID9021976 | Ethylene glycol phenyl ether | ethyleneglycol monophenyl ether | NSC1864NSC 1864 | Phenyl cellosolve | Phenylmonoglycol ether | STK802556 | CAS-122-99-6 | MFCD00002857 | PHENOXYETHANOL (II) | Plastiazan-41 | Fungal Terminator (veterinary)
Storage
Room temperature
Shipped In
Normal
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Size
Status
Price
Qty
100g
E109367-100g
4

$9.90

$14.90
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500g
E109367-500g
3
$24.90
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 18 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
DTXSID9021976 | Ethylene glycol phenyl ether | ethyleneglycol monophenyl ether | NSC1864NSC 1864 | Phenyl cellosolve | Phenylmonoglycol ether | STK802556 | CAS-122-99-6 | MFCD00002857 | PHENOXYETHANOL (II) | Plastiazan-41 | Fungal Terminator (veterinary)
Specifications & Purity
≥98%
Storage
Room temperature
Shipped In
Normal
Purity
≥98%
Names and Identifiers
Pubchem Sid488183142
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488183142
Canonical SmilesC1=CC=C(C=C1)OCCO
IUPAC Name2-phenoxyethanol
InChIKeyQCDWFXQBSFUVSP-UHFFFAOYSA-N
INCHI1S/C8H10O2/c9-6-7-10-8-4-2-1-3-5-8/h1-5,9H,6-7H2
Isomeric SMILES C1=CC=C(C=C1)OCCO
WGK Germany 1
RTECS KM0350000
Molecular Weight 138.16
Beilstein 1364011
Reaxy-Rn 1364011
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1364011&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassPhenol ethers
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentPhenol ethers
Alternative Parents Phenoxy compounds  Alkyl aryl ethers  Primary alcohols  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Phenoxy compound - Phenol ether - Alkyl aryl ether - Monocyclic benzene moiety - Ether - Organic oxygen compound - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Alcohol - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as phenol ethers. These are aromatic compounds containing an ether group substituted with a benzene ring.
External Descriptors aromatic ether - primary alcohol - hydroxyether
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXRA Tclin Retinoid X receptor alpha (3637 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TP53 Tchem Cellular tumor antigen p53 (48468 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lymphoblastoid cell (5959 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GNAS Tbio Guanine nucleotide-binding protein G(s), subunit alpha (103405 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RECQL Tbio ATP-dependent DNA helicase Q1 (5575 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

25 results found

Lot NumberCertificate TypeDateItem
D2624004Certificate of AnalysisMay 07, 2026 E109367
A2616201Certificate of AnalysisJan 20, 2026 E109367
A2616208Certificate of AnalysisJan 20, 2026 E109367
A2616209Certificate of AnalysisJan 20, 2026 E109367
A2616200Certificate of AnalysisJan 20, 2026 E109367
C1816002Certificate of AnalysisOct 14, 2025 E109367
L2025018Certificate of AnalysisOct 12, 2024 E109367
G2403489Certificate of AnalysisJul 12, 2024 E109367
G2403488Certificate of AnalysisJul 05, 2024 E109367
G2504098Certificate of AnalysisJul 05, 2024 E109367
G2403487Certificate of AnalysisJul 05, 2024 E109367
D2523109Certificate of AnalysisApr 29, 2024 E109367
J2528453Certificate of AnalysisJan 09, 2024 E109367
J2531135Certificate of AnalysisJan 09, 2024 E109367
L2326179Certificate of AnalysisJan 09, 2024 E109367
L2326180Certificate of AnalysisJan 09, 2024 E109367
L2326181Certificate of AnalysisJan 09, 2024 E109367
L2326182Certificate of AnalysisJan 09, 2024 E109367
I2305055Certificate of AnalysisSep 09, 2023 E109367
E2330129Certificate of AnalysisJun 02, 2023 E109367
B2301214Certificate of AnalysisFeb 07, 2023 E109367
D2301023Certificate of AnalysisDec 28, 2022 E109367
L2216924Certificate of AnalysisDec 28, 2022 E109367
B2301576Certificate of AnalysisDec 15, 2021 E109367
L2108523Certificate of AnalysisDec 15, 2021 E109367

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Chemical and Physical Properties
SolubilitySlightly soluble in water; Degree of Solubility in water: 27 g/l; Very soluble in Ether,Solution of sodium hydroxide in water,Alcohol
Refractive Index 1.536-1.54
Flash Point(°F)266 ℉
Flash Point(°C)130°C
Boil Point(°C)237°C
Melt Point(°C)11-13°C
Molecular Weight138.160 g/mol
XLogP31.200
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass138.068 Da
Monoisotopic Mass138.068 Da
Topological Polar Surface Area29.500 Ų
Heavy Atom Count10
Formal Charge0
Complexity77.300
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
A Practical Guide to Fragrance Compositions: Turning a Black-Box Formula into an Engineerable System—Compatibility, Stability, Controlled Release, Traceability, and Selection
From Water to Film: Film-Formation Mechanisms and Performance Development of Waterborne Emulsions and Dispersions
Solvents, Co-solvents, and Solubilization Systems in Home and Personal Care Formulations: Classification, Functions, and Selection Guide
Why Do Alcohols Differ in Function: Why Is Glycerol Mainly Moisturizing, Propylene Glycol Mainly Solubilizing, and Isopropyl Alcohol Fast-Drying? — Understanding Personal Care Formulation Functions from Structural Differences
Thickening, Suspension, Auxiliary Stabilization, and Agglomeration Mechanisms of Xanthan Gum in Personal Care Formulations: From Molecular Structure to Processing Applications
Analysis of Structural Differences in Diols: Moisturization, Co-solvency, Skin Feel, and Formulation Selection for Propylene Glycol, Butylene Glycol, and Medium- to Long-Chain 1,2-Alkanediols
Why Are Preservative Systems in Daily Chemical Products Effective? Common Types, Mechanisms of Action, and Factors Affecting Preservation Efficacy
Citations of This Product
References
1. Zi-Chen Jia, Duo Liu, Hai-Di Ma, Yu-Hui Cui, Hui-Min Li, Xia Li, Ying-Jin Yuan.  (2023)  Yeast Metabolic Engineering for Biosynthesis of Caffeic Acid-Derived Phenethyl Ester and Phenethyl Amide.  ACS Synthetic Biology,      [PMID:38016187] [10.1021/acssynbio.3c00413]
2. Zhihong Deng, Lifeng Zhao, Xiuxue Li, Chang-Yun Wang, Yue Zhou, Mengfei Li, Yingfei Li, Xianjun Fu.  (2023)  Folium crataegi boosts skin regeneration for burn injury in rats through multiple ways.  BIOMEDICINE & PHARMACOTHERAPY,      [PMID:37690389] [10.1016/j.biopha.2023.115457]
3. Youyou Yang, Jing Li, Jiangtao Xing, Weihai Xing, Chaohua Tang, Zhenghua Rao, Junmin Zhang.  (2022)  Untargeted Profiling and Differentiation of Volatiles in Varieties of Meat Using GC Orbitrap MS.  Foods,  11  (24): (3997).  [PMID:36553738] [10.3390/foods11243997]
4. Wan-Jun Long, Hai-Long Wu, Tong Wang, Ming-Yue Dong, Ru-Qin Yu.  (2020)  Interference-free analysis of multi-class preservatives in cosmetic products using alternating trilinear decomposition modeling of liquid chromatography diode array detection data.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2020.105847]
5. Xiao-Li Yin, Hui-Wen Gu, Ali R. Jalalvand, Ya-Juan Liu, Ying Chen, Tian-Qin Peng.  (2018)  Dealing with overlapped and unaligned chromatographic peaks by second-order multivariate calibration for complex sample analysis: Fast and green quantification of eight selected preservatives in facial masks.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:30243735] [10.1016/j.chroma.2018.09.019]
6. Shuyao Huang, Jianqiao Xu, Jiayi Wu, Haojia Hong, Guosheng Chen, Ruifen Jiang, Fang Zhu, Yuan Liu, Gangfeng Ouyang.  (2017)  Rapid detection of five anesthetics in tilapias by in vivo solid phase microextraction coupling with gas chromatography-mass spectrometry.  TALANTA,      [PMID:28391852] [10.1016/j.talanta.2017.03.045]
7. Jinjie Zhang, Jinlu Huang, Shanzhen Chen, Jing Tan, Xingyi Zhu, Yanqi Gao, Hui Zeng, Yong-An Zhang, Yang Zhou.  (2024)  Development and evaluation of the inactivated vaccine against Aeromonas schubertii in hybrid snakehead.  AQUACULTURE,      [PMID:] [10.1016/j.aquaculture.2024.741087]
8. Min Ouyang, Jiachang Wu, Xiongjian Huang, Guoping Dong.  (2024)  Enhanced rare-earth ion doping in silica glass by photopolymerization for microlaser.  JOURNAL OF LUMINESCENCE,      [PMID:] [10.1016/j.jlumin.2024.120704]
9. Han Kyoung-Moon, Woo In Suk, Park Chae Gyeong, Kim You Kyung, Yang Yoon Ji, Park Bo Reum, Choi Jang Duck, Son Kyung Hun.  (2024)  Simultaneous Analytical Method for Various Paraben and Alcohol Preservatives in Supposedly Natural and Organic Cosmetics by Off-line SPE–UHPLC–DAD and LC–MS/MS.  CHROMATOGRAPHIA,      [PMID:] [10.1007/s10337-024-04362-8]
10. Ruifeng Zhou, Zhou Yang, Xitong Yang, Menglong Zhang, Jiahui Gao, Sajjad Hussain, Qiuye Li.  (2025)  Design of amine-functionalized fly ash-based hierarchically porous SiO2 adsorbents and mechanistic insights into CO2 adsorption.  Journal of CO2 Utilization,      [PMID:] [10.1016/j.jcou.2025.103213]
11. Shao Li, Wang Lizhuang, Li Yan, Ma Laiji, Jiang Hong, Liu Fei, Jiang Shanshan, Bai Tianming, Yang Suzhen.  (2025)  Transcriptomic and metabolomic analyses of the antimicrobial activity of phenoxyethanol against phylotype IA1 and II Cutibacterium acnes.  JOURNAL OF APPLIED MICROBIOLOGY,      [PMID:40261688] [10.1093/jambio/lxaf089]
12. Qu Biqiong, Feng Menghan, Liu Lirong, Cong Shiyu, Cai Shengnan, Wang Tengteng, Qiao Yun, Shi Lixia, Liu Jie, Xiao Hongbin.  (2025)  Comprehensive and high-coverage glycerophospholipidomic analysis based on iterative quadrupole time-of-flight mass spectrometry and its application in cerebral ischemia–reperfusion injury.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,      [PMID:40327074] [10.1007/s00216-025-05884-2]
13. Chun Xiang, Cuiyi Liang, Wen Wang, Yu Zhang, Shiyou Xing, Xuesong Tan, Wei Liu, Baiquan Zeng, Wei Qi.  (2025)  Enhanced fractionation of woody biomass and efficient valorization via ternary acid-organic solvent system.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2025.117141]
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