Glucose oxidase is a flavin-dependent oxidoreductase that uses β-D-glucose as a specific substrate and flavin adenine dinucleotide (FAD) as a cofactor. It is widely found in certain molds and yeasts. This enzyme catalyzes the oxidation of β-D-glucose to D-glucono-δ-lactone while reducing ...
Glutamate dehydrogenase (GDH; EC 1.4.1.2 / 1.4.1.3 / 1.4.1.4) is a key oxidoreductase widely distributed in bacteria, fungi, plants, and animals. It catalyzes the reversible interconversion between L-glutamate and α-ketoglutarate (α-KG), coupled with the production or assimilation of ammonia ...
Cobalt (Co) is a highly “versatile” catalytic metal: it offers rich redox chemistry, can operate via both two-electron mechanisms and single-electron/radical pathways, and spans multiple application scenarios including homogeneous organic synthesis, energy electrocatalysis, and heterogeneous ...
Nonsteroidal anti-inflammatory drugs (Nonsteroidal Anti-inflammatory Drugs, NSAIDs) are a large and structurally diverse class of analgesic, antipyretic, and anti-inflammatory agents. The term “nonsteroidal” is used to distinguish them from glucocorticoids (steroidal anti-inflammatory ...
Organotin compounds are chemicals that contain at least one carbon–tin (C–Sn) bond in the molecule. By combining the tunability of organic substituents with the reactivity of the tin center, organotins are widely used in organic synthesis, materials chemistry, polymer science, and analytical ...
Lactate dehydrogenase (LDH, EC 1.1.1.27) is a key redox enzyme catalyzing the terminal, reversible “lactate–pyruvate” step of glycolysis, using NAD⁺/NADH as coenzyme. It is widely distributed in multiple tissues, including myocardium, liver, skeletal muscle, kidney, and red blood cells.
The complement system is one of the most important effector systems of humoral immunity and consists of a proteolytic enzyme cascade formed by multiple plasma proteins and membrane-bound proteins. As a core component of innate immunity, it is activated via the classical pathway, lectin pathway, ...
Pepsin is one of the earliest discovered and most extensively studied proteolytic enzymes. It belongs to the aspartic protease family and is generated from pepsinogen secreted by gastric chief cells upon activation in a strongly acidic environment. Its hallmark features are high activity at pH ...
In many experiments, the same challenge comes up again and again: the target molecule “works, but won’t dissolve.” Fat-soluble vitamins, hormones, hydrophobic small-molecule drugs, aromatic dyes, and similar compounds often show poor solubility in aqueous media (buffers, culture media). ...
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