β-Guanidinopropionic acid - Moligand™, ≥99% , CAS No.353-09-3

CAS: 353-09-3 Cat. No.: D137194 Formula: C₄H₉N₃O₂ Molecular Weight: 131.14 EC Number: 206-530-0

GRADE & PURITY Moligand™, ≥99%

Synonyms

beta-Guanidinopropionic acid | ss--Guanidinopropionic acid | Guanidinoproprionic-beta | FT-0602540 | HY-W015828 | SY066704 | 3-[(diaminomethylidene)amino]propanoic acid | N-carbamimidoyl-beta-alanine | N-(Aminomethyl)-beta-alanine | .beta.-Alanine, N-(ami

Storage

Room temperature,Argon charged

Shipped In

Normal

Overview

3-Guanidinopropionic acid is a creatine and GABA analog found in mammalian blood plasma, erythrocytes, urine, liver, kidney, and aorta. 3-Guanidinopropionic acid has been used to study endothelial cell contribution in wound healing, and as a hyperglycemia reliever in animal models.
A creatine and GABA analog found in mammalian blood plasma and erythrocytes.

Specifications

Synonyms

beta-Guanidinopropionic acid | ss--Guanidinopropionic acid | Guanidinoproprionic-beta | FT-0602540 | HY-W015828 | SY066704 | 3-[(diaminomethylidene)amino]propanoic acid | N-carbamimidoyl-beta-alanine | N-(Aminomethyl)-beta-alanine | .beta.-Alanine, N-(ami

Specifications & Purity

Moligand™, ≥99%

Biochemical and Physiological Mechanisms

β-Guanidinopropionic acid is studied for potential use during protein refolding as an anti-aggregatory molecule similar to L-arginine. β-Guanidinopropionic acid may be used to study its proliferative activity for endothelial cells contributing to wound he

Storage

Room temperature,Argon charged

Shipped In

Normal

Grade

Moligand™

Purity

≥99%

Names and Identifiers

• Pubchem Sid: 504754194
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504754194
• Canonical Smiles: C(CN=C(N)N)C(=O)O
• IUPAC Name: 3-(diaminomethylideneamino)propanoic acid
• InChIKey: KMXXSJLYVJEBHI-UHFFFAOYSA-N
• INCHI: 1S/C4H9N3O2/c5-4(6)7-2-1-3(8)9/h1-2H2,(H,8,9)(H4,5,6,7)
• Isomeric SMILES: C(CN=C(N)N)C(=O)O
• Molecular Weight: 131.14
• Reaxy-Rn: 25641161
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25641161&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Class Organonitrogen compounds
      • Subclass Guanidines

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Class: Organonitrogen compounds
• Subclass: Guanidines
• Intermediate Tree Nodes: Not available
• Direct Parent: Guanidines
• Alternative Parents: Propargyl-type 1,3-dipolar organic compounds Monocarboxylic acids and derivatives Carboxylic acids Carboximidamides Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Guanidine - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as guanidines. These are compounds containing a guanidine moiety, with the general structure (R1R2N)(R3R4N)C=N-R5.
• External Descriptors: guanidines

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

CKM Tbio Creatine kinase M (67 Activities)

Discover Target: CKM

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TPSAB1 Tclin Tryptase beta-1 (295 Activities)

Discover Target: TPSAB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC36A1 Tchem Proton-coupled amino acid transporter 1 (102 Activities)

Discover Target: SLC36A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A10 (235 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Gabrp GABA-A receptor; anion channel (5731 Activities)

Discover Target: Gabrp

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Sensitivity: Air Sensitive
• Melt Point(°C): 217 °C(dec.)
• Molecular Weight: 131.130 g/mol
• XLogP3: -1.800
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 131.069 Da
• Monoisotopic Mass: 131.069 Da
• Topological Polar Surface Area: 102.000 Ų
• Heavy Atom Count: 9
• Formal Charge: 0
• Complexity: 128.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Qianyi Li, Dongyang Li, Zhiqi Li, Qiong Liang, Patrick W. K. Fong, Yu Han, Kuan Liu, Jiangsheng Yu, Peng Bai, Tao Zhu, Yang Bai, Guang Yang, Zhiwei Ren, Gang Li.  (2025)  Tailoring Crystal Growth Regulation and Dual Passivation for Air-Processed Efficient Perovskite Solar Cells.  Advanced Science,  12  (14): (2407401).  [PMID:39973078] [10.1002/advs.202407401]

Frequently Asked Questions

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at room temperature under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships under standard ambient conditions. No temperature-controlled packaging is required.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 353-09-3, the molecular formula is C4H9N3O2, and the molecular weight is 131.14 g/mol. InChIKey KMXXSJLYVJEBHI-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.