HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a linear ubiquitin chain assembly complex (LUBAC) inhibitor with IC50 of 2.8 μM. HOIPIN-1 specifically generates Met1-linked linear ubiquitin chains through the ubiquitin ligase activity in HOIP, and activates the NF-kB pathway.
Specifications
Synonyms
JTP-0819958 | HOIP inhibitor-1
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a linear ubiquitin chain assembly complex (LUBAC) inhibitor with IC50 of 2.8 μM. HOIPIN-1 specifically generates Met1-linked linear ubiquitin chains through the ubiquitin ligase activity in HOIP, and activates t
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
Molecular Weight
304.27
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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Reviews
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