IMP-1088 - Moligand™, ≥98% , CAS No.2059148-82-0

CAS: 2059148-82-0 Cat. No.: I647608 Formula: C₂₅H₂₉F₂N₅O Molecular Weight: 453.53 PubChem CID: 132274735

GRADE & PURITY Moligand™, ≥98%

Synonyms

1-(5-(3,4-difluoro-2-(2-(1,3,5-Trimethyl-1H-pyrazol-4-yl)ethoxy)phenyl)-1-methyl-1H-indazol-3-yl)-N,N-dimethylmethanamine

Storage

Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

Specifications

Synonyms

1-(5-(3,4-difluoro-2-(2-(1,3,5-Trimethyl-1H-pyrazol-4-yl)ethoxy)phenyl)-1-methyl-1H-indazol-3-yl)-N,N-dimethylmethanamine

Specifications & Purity

Moligand™, ≥98%

Biochemical and Physiological Mechanisms

IMP-1088 is a potent human N-myristoyltransferases NMT1 and NMT2 dual inhibitor with IC 50 s of <1 nM for HsNMT1 and HsNMT2. IMP-1088 has a K d of <210 pM for HsNMT1. IMP-1088 efficiently blocks rhinovirus replication by blocking rhinovirus virus-encoded

Storage

Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Purity

≥98%

Names and Identifiers

• Isomeric SMILES: CC1=C(C(=NN1C)C)CCOC2=C(C=CC(=C2F)F)C3=CC4=C(C=C3)N(N=C4CN(C)C)C
• PubChem CID: 132274735
• Molecular Weight: 453.53

Mechanisms of Action

Chemical and Physical Properties

• Solubility: DMSO : 100 mg/mL (220.49 mM; Need ultrasonic)
• Sensitivity: Moisture sensitive
• Molecular Weight: 453.500 g/mol
• XLogP3: 4.300
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 453.234 Da
• Monoisotopic Mass: 453.234 Da
• Topological Polar Surface Area: 48.100 Ų
• Heavy Atom Count: 33
• Formal Charge: 0
• Complexity: 642.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1