IMR-1A - 10mM in DMSO , CAS No.331862-41-0

CAS: 331862-41-0 Cat. No.: I423397 Molecular Weight: 325.36
AVAILABLE TO ORDER
GRADE & PURITY 10mM in DMSO
Synonyms
Acetic acid,2-​[2-​methoxy-​4-​[(4-​oxo-​2-​thioxo-​5-​thiazolidinylidene)​methyl]​phenoxy]​-
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1ml
I423397-1ml
2

$81.90

$96.90
Save $15.00 (15.48%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Information

IMR-1A IMR-1A, an acid metabolite of IMR-1, is a potent inhibitor of Notch with IC50 of 0.5 μM and Kd of 2.9 μM. IMR-1A exhibits anti-tumor activity.

Targets

Notch (Cell-free assay); Notch (Cell-free assay) 0.5 μM; 2.9 μM(Kd)

Specifications

Synonyms
Acetic acid, 2-​[2-​methoxy-​4-​[(4-​oxo-​2-​thioxo-​5-​thiazolidinylidene)​methyl]​phenoxy]​-
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
IMR-1A, an acid metabolite of IMR-1, is a potent inhibitor of Notch with IC50 of 0.5 μM and Kd of 2.9 μM. IMR-1A exhibits anti-tumor activity.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Product Properties
ALogP2.29
hba_count4
HBD Count1
Rotatable Bond5
Names and Identifiers
Canonical SmilesCOC1=C(C=CC(=C1)C=C2C(=O)NC(=S)S2)OCC(=O)O
IUPAC Name2-[2-methoxy-4-[(E)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetic acid
InChIKeyDVBJNSKWHSGTDK-BJMVGYQFSA-N
INCHI1S/C13H11NO5S2/c1-18-9-4-7(2-3-8(9)19-6-11(15)16)5-10-12(17)14-13(20)21-10/h2-5H,6H2,1H3,(H,15,16)(H,14,17,20)/b10-5+
Molecular Weight 325.36
Reaxy-Rn 29764446
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29764446&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
DMSO(mg / mL) Max Solubility6
DMSO(mM) Max Solubility18.4411113843128
Water(mg / mL) Max Solubility<1
Solution Calculators
Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.