GRADE & PURITYCarrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Validated?Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated.Azide Free?Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory.PBS Only?PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers.≥95%(SDS-PAGE)See COA
Carrier Free,Azide Free,Validated,PBS Only,≥95%(SDS-PAGE),See COA Azide Free,Carrier Free,PBS Only,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at 2-8°C,Do not freeze Ships Wet ice,Do not freeze Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Rat anti Mouse/Human Integrin alpha 4/CD49D Antibody, Monoclonal (PS/2), could be used for Flow, in vivo VLA-4 neutralization, in vitro VLA-4 neutralization and so on. Application: Flow: Use at an assay dependent concentration. in vivo VLA-4 neutralization: Use at an assay dependent concentration. in vitro VLA-4 neutralization: Use at an assay dependent concentration. Protein Function Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
Specifications
Product Name
Integrin alpha 4/CD49D Rat mAb - Primary antibody, specific to Integrin alpha 4/CD49D, Rat IgG2b
Synonyms
CD49D | 269C wild type | CD49 antigen-like family member D | CD49d antigen | CD49d | CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor | IA4 | Integrin alpha 4 | integrin alpha-4 subunit | integrin alpha-4 | Integrin alpha-IV | integrin, alpha 4 (anti
Specifications & Purity
Carrier Free, Azide Free, Validated, PBS Only, ≥95%(SDS-PAGE), See COA
Host species
Rat
Specificity
Integrin alpha 4/CD49D
Immunogen
Mouse P815 mast cells
Conjugation
Unconjugated
Grade
Azide Free, Carrier Free, PBS Only, Validated
Isotype
Rat IgG2b
Light Chain Type
kappa
SDS-PAGE
150 kDa
Purification Method
Protein G purified
Concentration
See COA
Storage and Shipping
Shape
Liquid
Storage
Store at 2-8°C,Do not freeze
Shipped In
Wet ice,Do not freeze
Stability And Storage
Shipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon receipt, it is recommended to aliquot.
Images
Integrin alpha 4/CD49D Rat mAb (Ab110790) - Flow Cytometry Flow Cytometry analysis of human peripheral blood lymphocytes labelling Integrin alpha 4/CD49D with Integrin alpha 4/CD49D Rat mAb (Ab110790) conjugated with biotin (right panel) at 0.5 μg/mL for 1 hour at 4°C, compared with Rat IgG Isotype Control Antibody (Biotin) (Ab180310) (left panel) and detected with SA-PE (rp156150).
Integrin alpha 4/CD49D Rat mAb (Ab110790) - Flow Cytometry Flow Cytometry analysis of human peripheral blood lymphocytes labelling Integrin alpha 4/CD49D (red) with Integrin alpha 4/CD49D Rat mAb (Ab110790) conjugated with biotin at 0.5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Rat IgG Isotype Control Antibody (Biotin) (Ab180310). Black - Unlabelled control, cells without incubation with primary antibody.
Application
Application
Dilution info
Flow Cytometry
Use at an assay dependent concentration.
in vivo VLA-4 neutralization
Use at an assay dependent concentration.
in vitro VLA-4 neutralization
Use at an assay dependent concentration.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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