L-Lactic Acid - Moligand™, high-purity, ≥90% , CAS No.79-33-4

CAS: 79-33-4 Cat. No.: L107596 Formula: C₃H₆O₃ Molecular Weight: 90.08 Beilstein Registry Number: 1720251 EC Number: 201-196-2

GRADE & PURITY Moligand™, High-purity, ≥90%

Synonyms

L-(+)-Lactic acid, BioXtra, >=98% (titration) | L-Milchsaeure | (S)-2-Hydroxypropanoate | (S)-2-hydroxy-Propanoate | (S)-LACTIC ACID (EP MONOGRAPH) | L-(+)-Lactic acid 95% liquid | LACTIC ACID, L-(II) | (S)-LACTIC ACID [EP MONOGRAPH] | 1-Hydroxyethane 1-c

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Overview

L-(+)-Lactic acid is the only naturally occurring lactic acid in humans and mammals. Commercially, few bacteria like Lactobacillus casei, L. delbrueckii, Streptococcus lactisproduces L-Lactic acid by fermentation process. Lactic acid activates hydroxycarboxylic acid receptor, G-protein coupled receptor 81 (GPR81).
Usually used as a substrate for lactic acid dehydrogenase and lactate oxidase.

Specifications

Synonyms

L-(+)-Lactic acid, BioXtra, >=98% (titration) | L-Milchsaeure | (S)-2-Hydroxypropanoate | (S)-2-hydroxy-Propanoate | (S)-LACTIC ACID (EP MONOGRAPH) | L-(+)-Lactic acid 95% liquid | LACTIC ACID, L-(II) | (S)-LACTIC ACID [EP MONOGRAPH] | 1-Hydroxyethane 1-c

Specifications & Purity

Moligand™, high-purity, ≥90%

Biochemical and Physiological Mechanisms

L-(+)-Lactic acid is used as a substrate for lactic acid dehydrogenase and lactate oxidase.

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

High-purity, Moligand™

Purity

≥90%

Names and Identifiers

• Pubchem Sid: 508810632
• Canonical Smiles: C[C@H](O)C(O)=O
• IUPAC Name: (2S)-2-hydroxypropanoic acid
• InChIKey: JVTAAEKCZFNVCJ-REOHCLBHSA-N
• INCHI: 1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1
• Isomeric SMILES: C[C@@H](C(=O)O)O
• WGK Germany: 1
• RTECS: OD2800000
• UN Number: 3265
• Packing Group: III
• Molecular Weight: 90.08
• Beilstein: 1720251
• Reaxy-Rn: 1720251
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1720251&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Hydroxy acids and derivatives
      • Subclass Alpha hydroxy acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Hydroxy acids and derivatives
• Subclass: Alpha hydroxy acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Alpha hydroxy acids and derivatives
• Alternative Parents: Secondary alcohols Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha-hydroxy acid - Secondary alcohol - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as alpha hydroxy acids and derivatives. These are organic compounds containing a carboxylic acid substituted with a hydroxyl group on the adjacent carbon.
• External Descriptors: 2-hydroxypropanoic acid

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

HCAR1 Tchem Hydroxycarboxylic acid receptor 1 (0 Activities)

Discover Target: HCAR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MRC5 (9203 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A549 (127892 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC16A1 Tchem Monocarboxylate transporter 1 (146 Activities)

Discover Target: SLC16A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC16A3 Tchem Monocarboxylate transporter 4 (196 Activities)

Discover Target: SLC16A3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC16A7 Tchem Monocarboxylate transporter 2 (11 Activities)

Discover Target: SLC16A7

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

SARS-CoV-2 (38078 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in water (100 mg/ml), alcohol, acetone, and methanol. Insoluble in chloroform, petroleum, ether, and carbon disulfide.
• Sensitivity: Moisture & Light sensitive
• Refractive Index: 1.4260 to 1.4310
• Specific Rotation[α]: -10.0 to -15.0 deg(C=2.5, 1.5mol/L NaOH sol.)
• Flash Point(°C): 110 °C
• Boil Point(°C): 122 °C/20 hPa
• Melt Point(°C): 18 °C
• Molecular Weight: 90.080 g/mol
• XLogP3: -0.700
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 90.0317 Da
• Monoisotopic Mass: 90.0317 Da
• Topological Polar Surface Area: 57.500 Ų
• Heavy Atom Count: 6
• Formal Charge: 0
• Complexity: 59.100
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1