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· · COA & SDS available for every product · Same-day shipping on in-stock items Lazabemide - Moligand™, ≥98% , Inhibitor of Monoamine oxidase B, CAS No.103878-84-8, Inhibitor of Monoamine oxidase B
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Synonyms
5-Chloro-pyridine-2-carboxylic acid (2-amino-ethyl)-amide | LAZABEMIDE [USAN] | 2-Pyridinecarboxamide, N-(2-aminoethyl)-5-chloro- | JZXRLKWWVNUZRB-UHFFFAOYSA-N | MS-23081 | n-(2-aminoethyl)-5-chloro-2-pyridinecarboxamide | N-(2-Aminoethyl)-5-chloro-2-pyri
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview Lazabemide is a reversible and selective inhibitor of monoamine oxidase B (MAO-B) with Ki value of 7.9 nM.
Specifications Synonyms
5-Chloro-pyridine-2-carboxylic acid (2-amino-ethyl)-amide | LAZABEMIDE [USAN] | 2-Pyridinecarboxamide, N-(2-aminoethyl)-5-chloro- | JZXRLKWWVNUZRB-UHFFFAOYSA-N | MS-23081 | n-(2-aminoethyl)-5-chloro-2-pyridinecarboxamide | N-(2-Aminoethyl)-5-chloro-2-pyri
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
Lazabemide (Ro 19-6327) is a selective and reversible inhibitor of monoamine oxidase B (MAO-B) (IC50=0.03 μM), but less active against MAO-A (IC50>100 μM). High concentrations of Lazabemide have inhibitory effects on monoamine uptake, with IC50 values o
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Inhibitor of Monoamine oxidase B
Product Properties ALogP 0.533 hba_count 2 HBD Count 2 Rotatable Bond 3
Names and Identifiers Pubchem Sid 528771933 Canonical Smiles C1=CC(=NC=C1Cl)C(=O)NCCN IUPAC Name N-(2-aminoethyl)-5-chloropyridine-2-carboxamide InChIKey JZXRLKWWVNUZRB-UHFFFAOYSA-N INCHI 1S/C8H10ClN3O/c9-6-1-2-7(12-5-6)8(13)11-4-3-10/h1-2,5H,3-4,10H2,(H,11,13) Isomeric SMILES C1=CC(=NC=C1Cl)C(=O)NCCN Molecular Weight 199.64 Reaxy-Rn 6646689 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6646689&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Pyridines and derivatives Subclass Pyridinecarboxylic acids and derivatives Intermediate Tree Nodes Not available Direct Parent Pyridinecarboxamides Alternative Parents 2-heteroaryl carboxamides Aryl chlorides Heteroaromatic compounds Secondary carboxylic acid amides Amino acids and derivatives Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organochlorides Organic oxides Monoalkylamines Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents Pyridinecarboxamide - 2-heteroaryl carboxamide - Aryl chloride - Aryl halide - Heteroaromatic compound - Amino acid or derivatives - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid derivative - Azacycle - Organopnictogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Organochloride - Organohalogen compound - Primary aliphatic amine - Amine - Organic oxygen compound - Organic nitrogen compound - Organic oxide - Hydrocarbon derivative - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as pyridinecarboxamides. These are compounds containing a pyridine ring bearing a carboxamide. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties DMSO(mg / mL) Max Solubility 40 DMSO(mM) Max Solubility 169.419737399407 Water(mg / mL) Max Solubility 40 Water(mM) Max Solubility 169.419737399407 Molecular Weight 199.640 g/mol XLogP3 0.200 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 3 Rotatable Bond Count 3 Exact Mass 199.051 Da Monoisotopic Mass 199.051 Da Topological Polar Surface Area 68.000 Ų Heavy Atom Count 13 Formal Charge 0 Complexity 177.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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