Determine the necessary mass, volume, or concentration for preparing a solution.
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Ledipasvir acetone Ledipasvir (GS-5885) acetone is the active ingredient of Ledipasvir. Ledipasvir is a potent, oral active inhibitor of the hepatitis C virus (HCV) NS5A with EC50 of 31 pM and 4 pM against GT1a and GT1b replicon, respectively.
Targets
GT1b replicon (Cell-free assay); GT1a replicon (Cell-free assay) 4 pM(EC50); 31 pM(EC50)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Fluorenes |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Fluorenes |
| Alternative Parents | Valine and derivatives Alpha amino acid amides Benzimidazoles N-acylpiperidines N-acylpyrrolidines Tertiary carboxylic acid amides Heteroaromatic compounds Imidazoles Methylcarbamates Ketones Azacyclic compounds Hydrocarbon derivatives Alkyl fluorides Organonitrogen compounds Organofluorides Organic oxides |
| Molecular Framework | Not available |
| Substituents | Fluorene - Valine or derivatives - Alpha-amino acid amide - Alpha-amino acid or derivatives - N-acyl-piperidine - Benzimidazole - N-acylpyrrolidine - Piperidine - Azole - Heteroaromatic compound - Carbamic acid ester - Tertiary carboxylic acid amide - Pyrrolidine - Imidazole - Methylcarbamate - Carboxamide group - Ketone - Azacycle - Carboxylic acid derivative - Organoheterocyclic compound - Organooxygen compound - Organic nitrogen compound - Alkyl halide - Alkyl fluoride - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as fluorenes. These are compounds containing a fluorene moiety, which consists of two benzene rings connected through either a cyclopentane, cyclopentene, or cyclopenta-1,3-diene. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Dec 10, 2025 | L413102 | |
| Certificate of Analysis | Dec 10, 2025 | L413102 | |
| Certificate of Analysis | Dec 10, 2025 | L413102 | |
| Certificate of Analysis | Dec 10, 2025 | L413102 | |
| Certificate of Analysis | Dec 10, 2025 | L413102 |
| Solubility | Solubility (25°C) In vitro DMSO: 100 mg/mL (105.58 mM); Ethanol: 100 mg/mL (105.58 mM); Water: Insoluble; |
|---|---|
| DMSO(mg / mL) Max Solubility | 100 |
| DMSO(mM) Max Solubility | 105.587701144571 |
| Water(mg / mL) Max Solubility | <1 |
| Molecular Weight | 947.100 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 11 |
| Rotatable Bond Count | 12 |
| Exact Mass | 946.455 Da |
| Monoisotopic Mass | 946.455 Da |
| Topological Polar Surface Area | 192.000 Ų |
| Heavy Atom Count | 69 |
| Formal Charge | 0 |
| Complexity | 1850.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 6 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |