Targets & Pathways

Explore small molecules, screening libraries, and tool compounds for discovery research. Browse by target, pathway, or ligand family to quickly find inhibitors, agonists, and chemical probes, with searchable structure/CAS data and supporting documents (SDS/COA where available).

136,943 products

Ready-to-screen compound libraries and focused sets for hit discovery. Browse libraries by target class, pathway, scaffold, or application, and review size, format, and compound information to build screening panels.Customize Your Screening Library to choose compounds, format, and volume, and we’ll prepare a ready-to-use set for you.Customize Your Screening Library

Navigate small molecules by ligand family or scaffold to build focused sets and explore structure–activity relationships. This category groups related chemotypes, helping you select analogs, fragments, and tool molecules for discovery research.

ADC-focused building blocks and tools to support antibody–drug conjugate research. Explore payloads, linkers, conjugation reagents, and related small-molecule components (where available) for designing and evaluating ADC constructs.

PROTAC

2,815

PROTAC and targeted protein degradation tools for discovery research. Browse degrader-related ligands, linkers, and building blocks (where available) to assemble or screen PROTAC designs, with clear identifiers for efficient selection.

Explore pathway-focused tool compounds to study and modulate key signaling cascades. Browse small molecules grouped by signaling pathway to support mechanism studies, phenotypic assays, and target validation, with clear identifiers for fast searching.

Find bioactive small molecules organized by protein target (DTO). Quickly locate tool compounds for specific targets and compare identifiers such as structure, CAS, and synonyms—plus supporting documents —to build screening and validation sets.

Shop small molecules and tool compounds organized by disease area (DOID). Discover chemical probes, libraries, and related products mapped to therapeutic areas to help assemble compound sets for screening, pathway exploration, and model studies.

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  1. Uridine 5′-monophosphate
    CAS: 58-97-9 Formula: C9H13N2O9P Molecular Weight: 324.18
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: U424927
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    Technical Identifiers
    Synonyms
    U 5′-P UMP Uridylic acid
  2. VE-821, Inhibitor of ATR serine/threonine kinase
    CAS: 1232410-49-9 PubChem CID: 51000408 Formula: C18H16N4O3S Molecular Weight: 368.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: V408304
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    Synonyms
    2-Pyrazinecarboxamide, 3-amino-6-[4-(methylsulfonyl)phenyl]-N-phenyl-
  3. Urolithin A
    CAS: 1143-70-0 EC Number: 881-478-5 PubChem CID: 5488186 Formula: C13H8O4 Molecular Weight: 228.20
    Liquid 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: U420710
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    IUPAC Name
    3,8-dihydroxybenzo[c]chromen-6-one
    SMILES
    C1=CC2=C(C=C1O)C(=O)OC3=C2C=CC(=C3)O
    InChIKey
    RIUPLDUFZCXCHM-UHFFFAOYSA-N
    InChI
    1S/C13H8O4/c14-7-1-3-9-10-4-2-8(15)6-12(10)17-13(16)11(9)5-7/h1-6,14-15H
    Synonyms
    3,8-Dihydroxyurolithin | 3,8-dihydroxy-urolithin | FT-0778244 | 3,8-dihydroxy-6h-dibenzo[b,d]pyran-6-one | 3,8-Dihydr...
  4. VER-155008
    CAS: 1134156-31-2 PubChem CID: 25195348 Formula: C25H23Cl2N7O4 Molecular Weight: 556.4
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: V420680
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    IUPAC Name
    4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxymethyl]benzonitrile
    SMILES
    C1=CC(=CC=C1COCC2C(C(C(O2)N3C4=NC=NC(=C4N=C3NCC5=CC(=C(C=C5)Cl)Cl)N)O)O)C#N
    InChIKey
    ZXGGCBQORXDVTE-UMCMBGNQSA-N
    InChI
    1S/C25H23Cl2N7O4/c26-16-6-5-15(7-17(16)27)9-30-25-33-19-22(29)31-12-32-23(19)34(25)24-21(36)20(35)18(38-24)11-37-10-14-3-1-13(8-28)2-4-14/h1-7,12,18,2show more
    Synonyms
    4-({[(2R,3S,4R,5R)-5-(6-amino-8-{[(3,4-dichlorophenyl)methyl]amino}-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}m...
  5. Ursodeoxycholic acid(UDCA), Bile acid receptor FXR agonist
    CAS: 128-13-2 EC Number: 204-879-3 Formula: C24H40O4 Molecular Weight: 392.57
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: U407950
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    Synonyms
    (3α,​5β,​7β)​-3,​7-​dihydroxy-cholan-​24-​oic acid
  6. V-9302
    CAS: 1855871-76-9 PubChem CID: 127035871 Formula: C34H38N2O4 Molecular Weight: 538.68
    10mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: V408037
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    Synonyms
    Butanoic acid, 2-​amino-​4-​[bis[[2-​[(3-​methylphenyl)​methoxy]​phenyl]​methyl]​amino]​-​, (2S)​-
  7. VER-49009
    CAS: 940289-57-6 PubChem CID: 4369536 Formula: C19H18ClN3O4 Molecular Weight: 387.8
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: V427006
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    IUPAC Name
    3-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide
    SMILES
    CCNC(=O)C1=C(C(=NN1)C2=CC(=C(C=C2O)O)Cl)C3=CC=C(C=C3)OC
    InChIKey
    HUNAOTXNHVALTN-UHFFFAOYSA-N
    InChI
    1S/C19H18ClN3O4/c1-3-21-19(26)18-16(10-4-6-11(27-2)7-5-10)17(22-23-18)12-8-13(20)15(25)9-14(12)24/h4-9,24-25H,3H2,1-2H3,(H,21,26)(H,22,23)
    Synonyms
    VER-49009|558640-51-0|5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)-1H-PYRAZOLE-3-CARBOXAMIDE|940289-5...
  8. VER-50589
    CAS: 747413-08-7 PubChem CID: 135446210 Formula: C19H17ClN2O5 Molecular Weight: 388.8
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: V425808
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    Technical Identifiers
    IUPAC Name
    5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-1,2-oxazole-3-carboxamide
    SMILES
    CCNC(=O)C1=NOC(=C1C2=CC=C(C=C2)OC)C3=CC(=C(C=C3O)O)Cl
    InChIKey
    JXPCDMPJCKNLBY-UHFFFAOYSA-N
    InChI
    1S/C19H17ClN2O5/c1-3-21-19(25)17-16(10-4-6-11(26-2)7-5-10)18(27-22-17)12-8-13(20)15(24)9-14(12)23/h4-9,23-24H,3H2,1-2H3,(H,21,25)
    Synonyms
    VER-50589|747413-08-7|5-(5-Chloro-2,4-Dihydroxyphenyl)-N-Ethyl-4-(4-Methoxyphenyl)isoxazole-3-Carboxamide|VER50589|CH...
  9. Uridine 5'-monophosphate
    ◐ .Made to order · 8–12 wks Item #: U414407
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    Technical Identifiers
    SMILES
    OC1C(O)C(OC1CO[P](O)(O)=O)N2C=CC(=O)NC2=O
    Synonyms
    Uridylic acid | 5'-Uridylic acid | Uridine phosphate | 5'-UMP | Uridine 5'-phosphoric acid
  10. Urolithin B
    CAS: 1139-83-9 EC Number: 808-493-1 Formula: C13H8O3 Molecular Weight: 212.2
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: U420702
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    IUPAC Name
    3-hydroxybenzo[c]chromen-6-one
    SMILES
    C1=CC=C2C(=C1)C3=C(C=C(C=C3)O)OC2=O
    InChIKey
    WXUQMTRHPNOXBV-UHFFFAOYSA-N
    InChI
    1S/C13H8O3/c14-8-5-6-10-9-3-1-2-4-11(9)13(15)16-12(10)7-8/h1-7,14H
    Synonyms
    3-hydroxy-6H-benzo[c]chromen-6-one | urolithin B | EN300-186402 | m-Anisic aldehyde | 3-Hydroxy-6H-benzo[c]chromen-6-...
  11. VAS 2870
    CAS: 722456-31-7 EC Number: 804-251-4 PubChem CID: 4058452 Formula: C18H12N6OS Molecular Weight: 360.39
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: V425664
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    IUPAC Name
    2-(3-benzyltriazolo[4,5-d]pyrimidin-7-yl)sulfanyl-1,3-benzoxazole
    SMILES
    C1=CC=C(C=C1)CN2C3=C(C(=NC=N3)SC4=NC5=CC=CC=C5O4)N=N2
    InChIKey
    HZSOKHVVANONPV-UHFFFAOYSA-N
    InChI
    1S/C18H12N6OS/c1-2-6-12(7-3-1)10-24-16-15(22-23-24)17(20-11-19-16)26-18-21-13-8-4-5-9-14(13)25-18/h1-9,11H,10H2
    Synonyms
    XDB45631 | 1,3-benzoxazol-2-yl 3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl sulfide | NOX Inhibitor III, VAS2870 ...
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Frequently Asked Questions

What does the By Target/Pathway/Disease listing cover?
It groups compounds associated with targets in By Target/Pathway/Disease, organised so you can move from the pathway to an individual target and then to a specific chemotype. Each entry carries structure, CAS number, and reported activity.
How is By Target/Pathway/Disease organised?
By Target/Pathway/Disease is broken down into Compound Libraries, PROTACs, molecular glues and other degraders and Antibody-drug Conjugates(ADC). Compounds acting on more than one node appear under each relevant target.
How do I choose compounds for By Target/Pathway/Disease research?
For By Target/Pathway/Disease, pick a well-characterised reference compound for the node you want to perturb, and pair it with a structurally unrelated compound hitting the same target — that is the cleanest way to separate pathway effects from off-target ones. Check potency, selectivity, and cell permeability against your assay format. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find a specific compound within By Target/Pathway/Disease?
Search By Target/Pathway/Disease by compound name, CAS number, or SMILES, or drill down through the target listing. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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