Explore small molecules, screening libraries, and tool compounds for discovery research. Browse by target, pathway, or ligand family to quickly find inhibitors, agonists, and chemical probes, with searchable structure/CAS data and supporting documents (SDS/COA where available).
By Target / Pathway / Disease
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Ready-to-screen compound libraries and focused sets for hit discovery. Browse libraries by target class, pathway, scaffold, or application, and review size, format, and compound information to build screening panels.Customize Your Screening Library to choose compounds, format, and volume, and we’ll prepare a ready-to-use set for you.Customize Your Screening Library
Ligand families
24,635Navigate small molecules by ligand family or scaffold to build focused sets and explore structure–activity relationships. This category groups related chemotypes, helping you select analogs, fragments, and tool molecules for discovery research.
ADC-focused building blocks and tools to support antibody–drug conjugate research. Explore payloads, linkers, conjugation reagents, and related small-molecule components (where available) for designing and evaluating ADC constructs.
PROTAC
2,814PROTAC and targeted protein degradation tools for discovery research. Browse degrader-related ligands, linkers, and building blocks (where available) to assemble or screen PROTAC designs, with clear identifiers for efficient selection.
By Signaling Pathways
102,621Explore pathway-focused tool compounds to study and modulate key signaling cascades. Browse small molecules grouped by signaling pathway to support mechanism studies, phenotypic assays, and target validation, with clear identifiers for fast searching.
By Target (DTO)
19,694Find bioactive small molecules organized by protein target (DTO). Quickly locate tool compounds for specific targets and compare identifiers such as structure, CAS, and synonyms—plus supporting documents —to build screening and validation sets.
By Disease (DOID)
8,779Shop small molecules and tool compounds organized by disease area (DOID). Discover chemical probes, libraries, and related products mapped to therapeutic areas to help assemble compound sets for screening, pathway exploration, and model studies.
Products
- AMG 487CAS: 473719-41-4 Formula: C32H28F3N5O4 Molecular Weight: 603.59Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: A424120View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethoxy)phenyl]acetamide
- SMILES
- CCOC1=CC=C(C=C1)N2C(=O)C3=C(N=CC=C3)N=C2C(C)N(CC4=CN=CC=C4)C(=O)CC5=CC=C(C=C5)OC(F)(F)F
- InChIKey
- WQTKNBPCJKRYPA-OAQYLSRUSA-N
- InChI
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- Synonyms
- AMG 487|473719-41-4|AMG-487|355CGR2CBL|CHEMBL397983|Benzeneacetamide, N-((1R)-1-(3-(4-ethoxyphenyl)-3,4-dihydro-4-oxo...
- AMG 487CAS: 473719-41-4 Formula: C32H28F3N5O4 Molecular Weight: 603.59Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: A414114View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[(1R)-1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethoxy)phenyl]acetamide
- SMILES
- CCOC1=CC=C(C=C1)N2C(=O)C3=C(N=CC=C3)N=C2C(C)N(CC4=CN=CC=C4)C(=O)CC5=CC=C(C=C5)OC(F)(F)F
- InChIKey
- WQTKNBPCJKRYPA-OAQYLSRUSA-N
- InChI
- show more
- Synonyms
- (R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)ethyl)-N-(pyridin-3-ylmethyl)-2-(4-(trifluo...
- AMG 925CAS: 1401033-86-0 Formula: C26H29N7O2 Molecular Weight: 471.55● In Stock — US warehouse, ships to EU* Item #: A413772View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC1CCC(CC1)N2C3=C(C=CN=C3)C4=CN=C(N=C42)NC5=NC6=C(CN(CC6)C(=O)CO)C=C5
- InChIKey
- BBUVDDPUURMFOX-UHFFFAOYSA-N
- InChI
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- Synonyms
- AMG 925 | AMG925 | AMG-925 | NSC781514 | NSC-781514 | AS-17036 | J-018057 | FLX925 (AMG-925) | RB6Y814V4I | Ethanone,...
- AMG 9810, Channel blocker of TRPV1Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO◐ .Made to order · 8–12 wks Item #: A424649View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-3-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)prop-2-enamide
- SMILES
- CC(C)(C)C1=CC=C(C=C1)C=CC(=O)NC2=CC3=C(C=C2)OCCO3
- InChIKey
- GZTFUVZVLYUPRG-IZZDOVSWSA-N
- InChI
- 1S/C21H23NO3/c1-21(2,3)16-7-4-15(5-8-16)6-11-20(23)22-17-9-10-18-19(14-17)25-13-12-24-18/h4-11,14H,12-13H2,1-3H3,(H,22,23)/b11-6+
- Synonyms
- AMG-9810 | (e)-3-(4-tert-butylphenyl)-n-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylamide | BCP20822 | HMS3263D18 | 182...
- AHR 11652● In Stock — US warehouse, ships to EU* Item #: A353913View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 7-(4-bromobenzoyl)-1H-indole-2,3-dione
- SMILES
- C1=CC2=C(C(=C1)C(=O)C3=CC=C(C=C3)Br)NC(=O)C2=O
- InChIKey
- OKYHDBOEDYARAM-UHFFFAOYSA-N
- InChI
- 1S/C15H8BrNO3/c16-9-6-4-8(5-7-9)13(18)10-2-1-3-11-12(10)17-15(20)14(11)19/h1-7H,(H,17,19,20)
- Synonyms
- 7-(4-Bromobenzoyl)indoline-2,3-dione | SCHEMBL16796990 | AHR 11652 | Bromfenac Impurity 6 | 7-(4-BroMobenzoyl)- | BCP...
- AI-10-47● In Stock — US warehouse, ships to EU* Item #: A413399View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-pyridin-2-yl-6-(trifluoromethoxy)-1H-benzimidazole
- SMILES
- C1=CC=NC(=C1)C2=NC3=C(N2)C=C(C=C3)OC(F)(F)F
- InChIKey
- JSNWHSDKJSOXET-UHFFFAOYSA-N
- InChI
- 1S/C13H8F3N3O/c14-13(15,16)20-8-4-5-9-11(7-8)19-12(18-9)10-3-1-2-6-17-10/h1-7H,(H,18,19)
- AICAR (Acadesine), AMP-activated protein kinase, AMPK activatorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: A408470View ProductPricing & Pack Sizes
Technical Identifiers
- Synonyms
- NSC105823, AICA Riboside | 5-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-imidazol...
- AMD 3465 hexahydrobromide10mM in Water● In Stock — US warehouse, ships to EU* Item #: A422275View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(pyridin-2-ylmethyl)-1-[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methanamine;hexahydrobromide
- SMILES
- C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CNCC3=CC=CC=N3.Br.Br.Br.Br.Br.Br
- InChIKey
- ARHBIBDGWDRBJH-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- N-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanaminehexahydrobromide
- AMG 333CAS: 1416799-28-4 Formula: C20H12F5N3O4 Molecular Weight: 453.3310mM in DMSO● In Stock — US warehouse, ships to EU* Item #: A421542View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-[[(S)-(3-fluoropyridin-2-yl)-[3-fluoro-4-(trifluoromethoxy)phenyl]methyl]carbamoyl]pyridine-3-carboxylic acid
- SMILES
- C1=CC(=C(N=C1)C(C2=CC(=C(C=C2)OC(F)(F)F)F)NC(=O)C3=NC=C(C=C3)C(=O)O)F
- InChIKey
- QEBYISWYMFIXOZ-INIZCTEOSA-N
- InChI
- show more
- Synonyms
- AKOS037648724 | SCHEMBL14332808 | N17022 | BDBM50463850 | (S)-6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyrid...
- AMG 337, Inhibitor of CYP3A4;Inhibitor of MET proto-oncogene; receptor tyrosine kinaseCAS: 1173699-31-4 Formula: C23H22FN7O3 Molecular Weight: 463.46Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: A420776View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-[(1R)-1-[8-fluoro-6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(2-methoxyethoxy)-1,6-naphthyridin-5-one
- SMILES
- CC(C1=NN=C2N1C=C(C=C2F)C3=CN(N=C3)C)N4C=CC5=C(C4=O)C=C(C=N5)OCCOC
- InChIKey
- DWHXUGDWKAIASB-CQSZACIVSA-N
- InChI
- show more
- Synonyms
- 1,6-Naphthyridin-5(6H)-one, 6-((1R)-1-(8-fluoro-6-(1-methyl-1H-pyrazol-4-yl)-1,2,4-triazolo(4,3-a)pyridin-3-yl)ethyl)...
- ALW-II-41-27CAS: 1186206-79-0 Formula: C32H32F3N5O2S Molecular Weight: 607.6910mM in DMSO● In Stock — US warehouse, ships to EU* Item #: A420821View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[5-[[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-2-methylphenyl]-5-thiophen-2-ylpyridine-3-carboxamide
- SMILES
- CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)NC(=O)C4=CN=CC(=C4)C5=CC=CS5)C(F)(F)F
- InChIKey
- HYWXBDQAYLPMIX-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- ALW-II-41-27|1186206-79-0|N-(5-((4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)carbamoyl)-2-methylpheny...
- AM 095, Antagonist of LPA 1 receptorCAS: 1228690-36-5 Formula: C27H24N2O5 Molecular Weight: 456.49Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: A420988View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[4-[4-[3-methyl-4-[[(1R)-1-phenylethoxy]carbonylamino]-1,2-oxazol-5-yl]phenyl]phenyl]acetic acid
- SMILES
- CC1=NOC(=C1NC(=O)OC(C)C2=CC=CC=C2)C3=CC=C(C=C3)C4=CC=C(C=C4)CC(=O)O
- InChIKey
- LNDDRUPAICPXIN-GOSISDBHSA-N
- InChI
- show more
- Synonyms
- [1,1'-Biphenyl]-4acetic acid,4'-[3-methyl-4-[[[(1R)-1-phenylethoxy]carbonyl]amino]-5-isoxazolyl]- | 2-[4-[4-[3-methyl...
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Frequently Asked Questions
What does the By Target/Pathway/Disease listing cover?
It groups compounds associated with targets in By Target/Pathway/Disease, organised so you can move from the pathway to an individual target and then to a specific chemotype. Each entry carries structure, CAS number, and reported activity.
How is By Target/Pathway/Disease organised?
By Target/Pathway/Disease is broken down into Compound Libraries, PROTACs, molecular glues and other degraders and Antibody-drug Conjugates(ADC). Compounds acting on more than one node appear under each relevant target.
How do I choose compounds for By Target/Pathway/Disease research?
For By Target/Pathway/Disease, pick a well-characterised reference compound for the node you want to perturb, and pair it with a structurally unrelated compound hitting the same target — that is the cleanest way to separate pathway effects from off-target ones. Check potency, selectivity, and cell permeability against your assay format. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find a specific compound within By Target/Pathway/Disease?
Search By Target/Pathway/Disease by compound name, CAS number, or SMILES, or drill down through the target listing. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.