Explore pathway-focused tool compounds to study and modulate key signaling cascades. Browse small molecules grouped by signaling pathway to support mechanism studies, phenotypic assays, and target validation, with clear identifiers for fast searching.
By Signaling Pathways
Browse by type, application, or key specifications such as purity, grade, packaging, and handling requirements.
102,635 products
Shop by category
Anti-infection
12,257Browse pathway-oriented compounds relevant to anti-infection research, host–pathogen studies, and antimicrobial screening. Use this page to identify molecules associated with infection-related biology, cellular defense, and therapeutic discovery workflows.
Autophagy
2,910Browse pathway-focused compounds for autophagy research, lysosomal biology, and cellular stress-response studies. Use this page to compare molecules relevant to autophagy flux, organelle turnover, and mechanism-driven assay work.
Epigenetics
38,806Explore pathway-focused compounds for epigenetics research, including tools relevant to chromatin regulation and transcriptional control. Use this page to compare molecules used in target validation, mechanism studies, and cell-state modulation workflows.
JAK/STAT Signaling
1,726Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
Explore pathway-focused small molecules tied to metabolic enzyme and protease biology for mechanism studies, screening, and target validation. This page helps you review compounds relevant to catalytic pathways, substrate processing, and protease-driven cellular responses.
Find small molecules associated with PI3K/Akt/mTOR signaling for growth control, metabolism research, and oncology workflows. This category helps organize pathway modulators used in screening, target validation, and signal-transduction studies.
Stem Cell/Wnt
2,802Find small molecules associated with stem cell and Wnt signaling for differentiation studies, cell-fate control, and pathway research. This category helps organize compounds used in developmental biology, regenerative research, and signaling modulation.
Browse small molecules linked to cell cycle control and DNA damage pathways for oncology research, checkpoint studies, and assay development. Use this category to compare compounds relevant to proliferation control, repair mechanisms, and stress-response signaling.
GPCR/G Protein
9,673Browse small molecules mapped to GPCR and G protein signaling for receptor biology, pathway interrogation, and assay development. Use this page to compare modulators that help probe upstream signaling, second messengers, and receptor-driven responses.
MAPK/ERK Pathway
2,079Explore compounds linked to the MAPK/ERK pathway for signal-transduction research, proliferation studies, and response-pathway analysis. Use this page to compare modulators relevant to kinase cascades and downstream cellular signaling outputs.
Neuronal Signaling
10,271Explore small molecules connected to neuronal signaling for neurotransmission studies, neuropharmacology, and pathway research. This page helps organize compounds used to interrogate receptors, signaling nodes, and functional responses in neurobiology workflows.
Find small molecules associated with TGF-beta/Smad signaling for fibrosis research, differentiation studies, and pathway crosstalk analysis. Use this page to explore compounds relevant to growth control, developmental signaling, and translational biology.
Apoptosis
8,392Browse small molecules connected to apoptosis pathways for cell-death studies, stress-response research, and phenotypic screening. This category helps you compare compounds relevant to survival signaling, programmed cell death, and mechanism-based assays.
Cytoskeleton
1,392Find pathway-focused compounds for cytoskeleton research, including tools used in motility, trafficking, and cell-shape studies. Use this page to explore molecules relevant to structural dynamics and cytoskeleton-driven cellular behavior.
Find pathway-focused compounds for immunology and inflammation research, including tools relevant to cytokine signaling and immune regulation. This category supports screening and mechanism work in inflammatory pathways, immune-cell responses, and translational biology.
Find pathway-focused compounds related to membrane transporters and ion channels for transport biology, electrophysiology, and screening studies. This page helps you review modulators relevant to ion flow, substrate transport, and membrane-associated signaling.
NF-κB
2,563Browse pathway-focused small molecules for NF-κB research, inflammation studies, and transcriptional response assays. This category supports work on immune signaling, stress pathways, and mechanism-based screening around a central regulatory node.
Explore small molecules mapped to protein tyrosine kinase and receptor tyrosine kinase signaling for growth-factor biology and oncology research. This category supports focused screening and pathway studies around phosphorylation-driven signaling networks.
Explore small molecules linked to vitamin D–related and nuclear receptor signaling for endocrine biology, receptor studies, and transcription research. This category helps organize modulators tied to ligand-regulated pathways and downstream gene-control mechanisms.
Popular Products
- GSK 9027CAS: 1229096-88-1 Formula: C27H19F4N3O2S Molecular Weight: 525.52● In Stock — US warehouse, ships to EU* Item #: G288349View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-[1-(4-fluorophenyl)indazol-5-yl]-3-(trifluoromethyl)phenyl]-1-phenylmethanesulfonamide
- SMILES
- C1=CC=C(C=C1)CS(=O)(=O)NC2=CC(=C(C=C2)C3=CC4=C(C=C3)N(N=C4)C5=CC=C(C=C5)F)C(F)(F)F
- InChIKey
- DXBJGDVBQPEMOB-UHFFFAOYSA-N
- InChI
- 1S/C27H19F4N3O2S/c28-21-7-10-23(11-8-21)34-26-13-6-19(14-20(26)16-32-34)24-12-9-22(15-25(24)27(29,30)31)33-37(35,36)17-18-4-2-1-3-5-18/h1-16,33H,17H2
- Synonyms
- N-[4-[1-(4-Fluorophenyl)-1H-indazol-5-yl-3-(trifluoromethyl)phenyl]benzenesulfonamide
- GSK J5 HCl◐ .Made to order · 8–12 wks Item #: G288263View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- ethyl 3-[[2-pyridin-3-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate;hydrochloride
- SMILES
- CCOC(=O)CCNC1=CC(=NC(=N1)C2=CN=CC=C2)N3CCC4=CC=CC=C4CC3.Cl
- InChIKey
- QQHQMHJAOKADED-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester hydrochloride
- GW 1929 hydrochloride◐ .Made to order · 8–12 wks Item #: G286659View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (2S)-2-(2-benzoylanilino)-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]propanoic acid;hydrochloride
- SMILES
- CN(CCOC1=CC=C(C=C1)CC(C(=O)O)NC2=CC=CC=C2C(=O)C3=CC=CC=C3)C4=CC=CC=N4.Cl
- InChIKey
- KXNKIKXTGRMLEY-YCBFMBTMSA-N
- InChI
- show more
- Synonyms
- N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosine hydrochloride
- NBI 35965 hydrochloride◐ .Made to order · 8–12 wks Item #: N288172View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (10S)-9-(cyclopropylmethyl)-3-(2,4-dichlorophenyl)-10-ethyl-6-methyl-1,2,5,9-tetrazatricyclo[6.3.1.04,12]dodeca-2,4,6,8(12)-tetraene;hydrochloride
- SMILES
- CCC1CN2C3=C(N1CC4CC4)C=C(N=C3C(=N2)C5=C(C=C(C=C5)Cl)Cl)C.Cl
- InChIKey
- LNYUWBPFYXPUIO-RSAXXLAASA-N
- InChI
- show more
- Synonyms
- 1782228-59-4 | DTXSID10849508 | (10S)-9-(cyclopropylmethyl)-3-(2,4-dichlorophenyl)-10-ethyl-6-methyl-1,2,5,9-tetrazat...
- PFI 4, bromodomain and PHD finger containing 1Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%● In Stock — US warehouse, ships to EU* Item #: P287481View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(1,3-dimethyl-2-oxo-6-pyrrolidin-1-ylbenzimidazol-5-yl)-2-methoxybenzamide
- SMILES
- CN1C2=C(C=C(C(=C2)NC(=O)C3=CC=CC=C3OC)N4CCCC4)N(C1=O)C
- InChIKey
- QCIJLRJBZDBVDB-UHFFFAOYSA-N
- InChI
- 1S/C21H24N4O3/c1-23-17-12-15(22-20(26)14-8-4-5-9-19(14)28-3)16(25-10-6-7-11-25)13-18(17)24(2)21(23)27/h4-5,8-9,12-13H,6-7,10-11H2,1-3H3,(H,22,26)
- Synonyms
- N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-pyrrolidinyl)-1H-benzimidazol-5-yl]-2-methoxybenzamide
- GSK1904529ACAS: 1089283-49-7 Formula: C44H47F2N9O5S Molecular Weight: 851.96Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: G127237View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- show more
- SMILES
- CCC1=CC(=C(C=C1N2CCC(CC2)N3CCN(CC3)S(=O)(=O)C)OC)NC4=NC=CC(=N4)C5=C(N=C6N5C=CC=C6)C7=CC(=C(C=C7)OC)C(=O)NC8=C(C=CC=C8F)F
- InChIKey
- MOSKATHMXWSZTQ-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- MOSKATHMXWSZTQ-UHFFFAOYSA-N | SB18897 | Trifluralin [ANSI:BSI:ISO] | AMY24202 | A24618 | GSK 4529 | IGF-1R inhibitor ...
- GT 949CAS: 460330-27-2 Formula: C30H37N7O2 Molecular Weight: 527.66● In Stock — US warehouse, ships to EU* Item #: G286915View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[(4-cyclohexylpiperazin-1-yl)-[1-(2-phenylethyl)tetrazol-5-yl]methyl]-6-methoxy-1H-quinolin-2-one
- SMILES
- COC1=CC2=C(C=C1)NC(=O)C(=C2)C(C3=NN=NN3CCC4=CC=CC=C4)N5CCN(CC5)C6CCCCC6
- InChIKey
- ZVWPOIUAPXDLMB-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- GT949 | GT-949 | 3-[(4-Cyclohexyl-1-piperazinyl)[1-(2-phenylethyl)-1H-tetrazol-5-yl]methyl]-6-methoxy-2(1H)-quinolino...
- GTP-γ-S-Li4Solid ≥90%● In Stock — US warehouse, ships to EU* Item #: G276049View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- tetralithium;[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] dioxidophosphinothioyl phosphate
- SMILES
- [Li+].[Li+].[Li+].[Li+].C1=NC2=C(N1C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=S)([O-])[O-])O)O)N=C(NC2=O)N
- InChIKey
- AMQXJFWJOAWCPV-ZVQJTLEUSA-J
- InChI
- show more
- Synonyms
- Gtp-gamma-S-tetralithium | EINECS 305-606-1 | tetralithium;[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydr...
- GTS-21 dihydrochloride (DMBX-A)● In Stock — US warehouse, ships to EU* Item #: G275216View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[(5E)-5-[(2,4-dimethoxyphenyl)methylidene]-3,4-dihydro-2H-pyridin-6-yl]pyridine;dihydrochloride
- SMILES
- COC1=CC(=C(C=C1)C=C2CCCN=C2C3=CN=CC=C3)OC.Cl.Cl
- InChIKey
- BXKYFUGAAFLYJL-BXGYHSFXSA-N
- InChI
- 1S/C19H20N2O2.2ClH/c1-22-17-8-7-14(18(12-17)23-2)11-15-5-4-10-21-19(15)16-6-3-9-20-13-16;;/h3,6-9,11-13H,4-5,10H2,1-2H3;2*1H/b15-11+;;
- Synonyms
- AKOS037515500 | SCHEMBL8003 | DMXB | DANSYLAMIDE [FOR FLUOROMETRY] | Gts 21 | GTS-21 2HCl | GTS-21 (dihydrochloride) ...
- Lysine acetate● In Stock — US warehouse, ships to EU* Item #: L111313View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- acetic acid;(2S)-2,6-diaminohexanoic acid
- SMILES
- CC(=O)O.C(CCN)CC(C(=O)O)N
- InChIKey
- RRNJROHIFSLGRA-JEDNCBNOSA-N
- InChI
- 1S/C6H14N2O2.C2H4O2/c7-4-2-1-3-5(8)6(9)10;1-2(3)4/h5H,1-4,7-8H2,(H,9,10);1H3,(H,3,4)/t5-;/m0./s1
- Synonyms
- Lysine, monoacetate | L-LYSINE, MONOACETATE | MFCD00039069 | TTL6G7LIWZ | L-Lysine Acetate, Pharmaceutical Secondary ...
- Lomerizine DihydrochlorideCAS: 101477-54-7 EC Number: 686-037-9 PubChem CID: 122125 Formula: C27H30F2N2O3·2HCl Molecular Weight: 541.46● In Stock — US warehouse, ships to EU* Item #: L157774View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine;dihydrochloride
- SMILES
- COC1=C(C(=C(C=C1)CN2CCN(CC2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F)OC)OC.Cl.Cl
- InChIKey
- LOGVKVSFYBBUAJ-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- 101477-54-7, 101477-55-8(free base) | Tox21_112172 | Lomerizine Dihydrochloride, 98% | Terranas (TN) | DTXCID9026427 ...
- LumbrokinaseCAS: 556743-18-1Solid EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. ≥12000U/mg● In Stock — US warehouse, ships to EU* Item #: L115121View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Earthworm
- Bioactivity
- ≥12000U/mg
Fast Shipping Same-day shipping on in-stock items
Technical Details Quality & specification info on every product page
Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What does the By Signaling Pathways listing cover?
It groups compounds associated with targets in By Signaling Pathways, organised so you can move from the pathway to an individual target and then to a specific chemotype. Each entry carries structure, CAS number, and reported activity.
What does By Signaling Pathways cover?
By Signaling Pathways is a top-level listing in our catalogue. Use the filters and search on the listing page to narrow by the attributes that matter for your work, or browse the neighbouring categories from the main navigation.
How do I choose compounds for By Signaling Pathways research?
For By Signaling Pathways, pick a well-characterised reference compound for the node you want to perturb, and pair it with a structurally unrelated compound hitting the same target — that is the cleanest way to separate pathway effects from off-target ones. Check potency, selectivity, and cell permeability against your assay format. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find a specific compound within By Signaling Pathways?
Search By Signaling Pathways by compound name, CAS number, or SMILES, or drill down through the target listing. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.