MAP3K
47 products
Products
- CP 43CAS: 850467-66-2 Formula: C25H24N2O2 Molecular Weight: 384.4710mM in DMSO● In Stock — US warehouse, ships to EU* Item #: C426251View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-4-phenylbenzamide
- SMILES
- C1CC(C2=CC=CC=C2C1)NC(=O)CNC(=O)C3=CC=C(C=C3)C4=CC=CC=C4
- InChIKey
- WQKXOAJVNFOHNZ-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- N-(2-Oxo-2-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)ethyl)-[1,1'-biphenyl]-4-carboxamide
- CP 43CAS: 850467-66-2 Formula: C25H24N2O2 Molecular Weight: 384.47● In Stock — US warehouse, ships to EU* Item #: C287360View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-4-phenylbenzamide
- SMILES
- C1CC(C2=CC=CC=C2C1)NC(=O)CNC(=O)C3=CC=C(C=C3)C4=CC=CC=C4
- InChIKey
- WQKXOAJVNFOHNZ-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- N-(2-Oxo-2-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)ethyl)-[1,1'-biphenyl]-4-carboxamide | TAO Kinase inhibitor 1
- Demethyl-CoclaurineCAS: 5843-65-2 Formula: C16H17NO3 Molecular Weight: 271.3110mM in DMSO● In Stock — US warehouse, ships to EU* Item #: D424889View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
- SMILES
- C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=C(C=C3)O
- InChIKey
- WZRCQWQRFZITDX-UHFFFAOYSA-N
- InChI
- 1S/C16H17NO3/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14/h1-4,8-9,14,17-20H,5-7H2
- Synonyms
- 6,7-Dihydroxy-1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline | tris-(o-tolyl)phosphine | AC-26394 | FS-81...
- Demethyl-CoclaurineCAS: 5843-65-2 Formula: C16H17NO3 Molecular Weight: 271.31● In Stock — US warehouse, ships to EU* Item #: D412891View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
- SMILES
- C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=C(C=C3)O
- InChIKey
- WZRCQWQRFZITDX-UHFFFAOYSA-N
- InChI
- 1S/C16H17NO3/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14/h1-4,8-9,14,17-20H,5-7H2
- Synonyms
- 6,7-Dihydroxy-1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline | tris-(o-tolyl)phosphine | AC-26394 | FS-81...
- GS-444217, Inhibitor of mitogen-activated protein kinase kinase kinase 5CAS: 1262041-49-5 Formula: C23H21N7O Molecular Weight: 411.46Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: G421098View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-(4-cyclopropylimidazol-1-yl)-N-[3-(4-cyclopropyl-1,2,4-triazol-3-yl)phenyl]pyridine-2-carboxamide
- SMILES
- C1CC1C2=CN(C=N2)C3=CC(=NC=C3)C(=O)NC4=CC=CC(=C4)C5=NN=CN5C6CC6
- InChIKey
- ZGCMQKWOUIMBEP-UHFFFAOYSA-N
- InChI
- 1S/C23H21N7O/c31-23(20-11-19(8-9-24-20)29-12-21(25-13-29)15-4-5-15)27-17-3-1-2-16(10-17)22-28-26-14-30(22)18-6-7-18/h1-3,8-15,18H,4-7H2,(H,27,31)
- Synonyms
- GS444217 | GS 444217 | ASK1-IN-1
- GSK 114CAS: 1301761-96-5 Formula: C19H23N5O4S Molecular Weight: 417.48Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: G412389View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[(6,7-dimethoxyquinazolin-4-yl)amino]-4-(dimethylamino)-N-methylbenzenesulfonamide
- SMILES
- CNS(=O)(=O)C1=CC(=C(C=C1)N(C)C)NC2=NC=NC3=CC(=C(C=C32)OC)OC
- InChIKey
- YUSROMRPOFFTMX-UHFFFAOYSA-N
- InChI
- 1S/C19H23N5O4S/c1-20-29(25,26)12-6-7-16(24(2)3)15(8-12)23-19-13-9-17(27-4)18(28-5)10-14(13)21-11-22-19/h6-11,20H,1-5H3,(H,21,22,23)
- Synonyms
- GSK-114 | 3-((6,7-Dimethoxyquinazolin-4-yl)amino)-4-(dimethylamino)-N-methylbenzenesulfonamide
- GS-444217, Inhibitor of mitogen-activated protein kinase kinase kinase 5CAS: 1262041-49-5 Formula: C23H21N7O Molecular Weight: 411.46Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: G412159View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-(4-cyclopropylimidazol-1-yl)-N-[3-(4-cyclopropyl-1,2,4-triazol-3-yl)phenyl]pyridine-2-carboxamide
- SMILES
- C1CC1C2=CN(C=N2)C3=CC(=NC=C3)C(=O)NC4=CC=CC(=C4)C5=NN=CN5C6CC6
- InChIKey
- ZGCMQKWOUIMBEP-UHFFFAOYSA-N
- InChI
- 1S/C23H21N7O/c31-23(20-11-19(8-9-24-20)29-12-21(25-13-29)15-4-5-15)27-17-3-1-2-16(10-17)22-28-26-14-30(22)18-6-7-18/h1-3,8-15,18H,4-7H2,(H,27,31)
- Synonyms
- GS444217 | GS 444217 | ASK1-IN-1
- Higenamine hydrochlorideCAS: 11041-94-4 Formula: C16H17NO3.HCl Molecular Weight: 307.7710mM in DMSO● In Stock — US warehouse, ships to EU* Item #: H420598View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol;hydrochloride
- SMILES
- C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=C(C=C3)O.Cl
- InChIKey
- SWWQQSDRUYSMAR-UHFFFAOYSA-N
- InChI
- 1S/C16H17NO3.ClH/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14;/h1-4,8-9,14,17-20H,5-7H2;1H
- Synonyms
- 6,7-ISOQUINOLINEDIOL, 1,2,3,4-TETRAHYDRO-1-((4-HYDROXYPHENYL)METHYL)-, HYDROCHLORIDE, (+/-)- | DTXSID10911673 | 6,7-d...
- Higenamine hydrochlorideSolid ≥99%● In Stock — US warehouse, ships to EU* Item #: H413084View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol;hydrochloride
- SMILES
- C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=C(C=C3)O.Cl
- InChIKey
- SWWQQSDRUYSMAR-UHFFFAOYSA-N
- InChI
- 1S/C16H17NO3.ClH/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14;/h1-4,8-9,14,17-20H,5-7H2;1H
- Synonyms
- 6,7-ISOQUINOLINEDIOL, 1,2,3,4-TETRAHYDRO-1-((4-HYDROXYPHENYL)METHYL)-, HYDROCHLORIDE, (+/-)- | DTXSID10911673 | 6,7-d...
- N-Des(aminocarbonyl) AZ-TAK1 inhibitorCAS: 494772-87-1 Formula: C16H19N3O2S Molecular Weight: 317.41◐ .Made to order · 8–12 wks Item #: D275539View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-amino-5-[4-(morpholin-4-ylmethyl)phenyl]thiophene-2-carboxamide
- SMILES
- C1COCCN1CC2=CC=C(C=C2)C3=CC(=C(S3)C(=O)N)N
- InChIKey
- UNTPTSFVGRSTDC-UHFFFAOYSA-N
- InChI
- 1S/C16H19N3O2S/c17-13-9-14(22-15(13)16(18)20)12-3-1-11(2-4-12)10-19-5-7-21-8-6-19/h1-4,9H,5-8,10,17H2,(H2,18,20)
- Synonyms
- 3-Amino-5-[4-(morpholin-4-ylmethyl)phenyl]thiophene-2-carboxamide | N-Des(aminocarbonyl) AZ-TAK1 Inhibitor | starbld0...
- NG25, Inhibitor of C-terminal Src kinase;Inhibitor of LYN proto-oncogene; Src family tyrosine kinase;Inhibitor of mitogen-activated protein kinase kinase kinase 7;Inhibitor of mitogen-activated protein kinase kinase kinase kinase 2;Inhibitor of SRC proto-oncogeMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: N421221View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide
- SMILES
- CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=C5C=CNC5=NC=C4)C(F)(F)F
- InChIKey
- SMPGEBOIKULBCT-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- AC-35824 | Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]py...
- NQDI 1CAS: 175026-96-7 Formula: C19H13NO4 Molecular Weight: 319.3110mM in DMSO● In Stock — US warehouse, ships to EU* Item #: N422144View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- ethyl 8,15-dioxo-14-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(16),2,4,6,9(17),10,12-heptaene-16-carboxylate
- SMILES
- CCOC(=O)C1=C2C3=CC=CC=C3C(=O)C4=C2C(=CC=C4)NC1=O
- InChIKey
- UFJGFNHRMPMALC-UHFFFAOYSA-N
- InChI
- 1S/C19H13NO4/c1-2-24-19(23)16-15-10-6-3-4-7-11(10)17(21)12-8-5-9-13(14(12)15)20-18(16)22/h3-9H,2H2,1H3,(H,20,22)
- Synonyms
- 2,7-Dihydro-2,7-dioxo-3H-naphtho[1,2,3-de]quinoline-1-carboxylic acid ethyl ester; ethyl 2,7-dioxo-3,7-dihydro-2H-nap...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the MAP3K listing put together?
It draws on reported MAP3K annotations within MAPK/ERK Pathway and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a MAP3K modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the MAP3K entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for MAP3K compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For MAP3K work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the MAP3K compound I need is not listed?
Search by CAS number or SMILES first, since analogs of MAP3K compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.












