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LY3405105 - ≥95% , CAS No.2326428-25-3

CAS: 2326428-25-3 Cat. No.: L413667 Molecular Weight: 497.63
COA
LY3405105 - ≥95% CAS No(2326428-25-3) by Aladdin Scientific
AVAILABLE TO ORDER
GRADE & PURITY ≥95%
Synonyms
1-​Piperidinecarboxylic acid,4-​[[5-​methyl-​3-​(1-​methylethyl)​pyrazolo[1,​5-​a]​pyrimidin-​7-​yl]​amino]​-​,1-​[(2E)​-​4-​(dimethylamino)​-​1-​oxo-​2-​buten-​1-​yl]​-​3-​pyrrolidinyl ester
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
L413667-5mg
3

$179.90

$233.90
Save $54.00 (23.09%)
25mg
L413667-25mg
2

$582.90

$755.90
Save $173.00 (22.89%)
50mg
L413667-50mg
2

$847.90

$1,098.90
Save $251.00 (22.84%)
100mg
L413667-100mg
2

$1,323.90

$1,716.90
Save $393.00 (22.89%)
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Overview Specifications Names and Identifiers Documentation Advanced Data 3D Structure Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews
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Why this grade

≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Information

LY3405105 LY3405105 is an orally active CDK7 inhibitor with an IC50 of 92.8 nM. LY3405105 shows potential antineoplastic activity.

Specifications

Synonyms
1-​Piperidinecarboxylic acid, 4-​[[5-​methyl-​3-​(1-​methylethyl)​pyrazolo[1, ​5-​a]​pyrimidin-​7-​yl]​amino]​-​, 1-​[(2E)​-​4-​(dimethylamino)​-​1-​oxo-​2-​buten-​1-​yl]​-​3-​pyrrolidinyl ester
Specifications & Purity
≥95%
Biochemical and Physiological Mechanisms
LY3405105 is an orally active CDK7 inhibitor with an IC50 of 92.8 nM. LY3405105 shows potential antineoplastic activity.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Purity
≥95%
Names and Identifiers
Pubchem Sid504773536
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504773536
Canonical SmilesCC1=NC2=C(C=NN2C(=C1)NC3CCN(CC3)C(=O)OC4CCN(C4)C(=O)C=CCN(C)C)C(C)C
IUPAC Name[1-[(E)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl] 4-[(5-methyl-3-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-yl)amino]piperidine-1-carboxylate
InChIKeyGRDAHPJRLCTJNA-VOTSOKGWSA-N
INCHI1S/C26H39N7O3/c1-18(2)22-16-27-33-23(15-19(3)28-25(22)33)29-20-8-12-31(13-9-20)26(35)36-21-10-14-32(17-21)24(34)7-6-11-30(4)5/h6-7,15-16,18,20-21,29H,8-14,17H2,1-5H3/b7-6+
Molecular Weight 497.63
Reaxy-Rn 34497862
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=34497862&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

3D Structure
Interactive Chemical Structure Model





Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateItem
C2624091Certificate of AnalysisApr 07, 2026 L413667
C2624014Certificate of AnalysisApr 07, 2026 L413667
C2303718Certificate of AnalysisDec 12, 2025 L413667
C2303719Certificate of AnalysisDec 12, 2025 L413667
C2303720Certificate of AnalysisDec 12, 2025 L413667
C2303724Certificate of AnalysisDec 12, 2025 L413667
Chemical and Physical Properties
SolubilitySolubility (25°C) In vitro DMSO: 99 mg/mL (198.94 mM); Ethanol: 99 mg/mL (198.94 mM); Water: Insoluble;
Solution Calculators
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