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Lys-CoA TFA - ≥99% , CAS No.L658820
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Storage
Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
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Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Lys-CoA TFA is a selective p300 histone acetyltransferase (HAT) inhibitor ( IC 50 =50-500 nM). Lys-CoA TFA displays >100-fold selectivity for p300 over PCAF (IC 50 =200 μM). Lys-CoA TFA inhibits p300 HAT activity-dependent transcriptional activation.
Appearance:Solid
IC50& Target:p300 50-500 nM (IC 50 )
In Vitro:Lys-CoA TFA (0.1 and 1 mM; 60 hours) induces a senescent phenotype in human normal melanocytes. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Proliferation AssayCell Line: Normal human melan
Biological Activity:Lys-CoA TFA is a selective p300 histone acetyltransferase (HAT) inhibitor ( IC 50 =50-500 nM). Lys-CoA TFA displays >100-fold selectivity for p300 over PCAF (IC 50 =200 μM). Lys-CoA TFA inhibits p300 HAT activity-dependent transcriptional activation.
Specifications
Specifications & Purity
≥99%
Storage
Store at -20°C, Desiccated
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Purity
≥99%
Names and Identifiers
| Molecular Weight | 1108.82 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Solubility | H2O : 70 mg/mL (63.13 mM; Need ultrasonic) |
|---|
Solution Calculators
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Customer Reviews
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