m-PEG2-Tos - ≥95% , CAS No.50586-80-6

CAS: 50586-80-6 Cat. No.: M412483 Formula: C₁₂H₁₈O₅S Molecular Weight: 274.34 EC Number: 633-362-9

GRADE & PURITY ≥95%

Synonyms

2-(2-methoxy-ethoxy)ethyl 4-toluenesulfonate | 2-(2-methoxyethoxy)ethyl 4-toluenesulfonate | HY-42745 | 1-methyl -L-tryptophan | m-PEG2-Tos | 2,6-dichlor-4-methylpyridin-3-carboxylic acid | SCHEMBL361530 | AS-69959 | 2-(2-methoxyethoxy)ethyl tosylate | m-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Application

Antibody Drug Conjugates(ADC), Drug Delivery, Surface Modification, PEGylation of Protein, Peptide & Oligo

Overview

Information

m-PEG2-Tos is an uncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

Specifications

Synonyms

2-(2-methoxy-ethoxy)ethyl 4-toluenesulfonate | 2-(2-methoxyethoxy)ethyl 4-toluenesulfonate | HY-42745 | 1-methyl -L-tryptophan | m-PEG2-Tos | 2,6-dichlor-4-methylpyridin-3-carboxylic acid | SCHEMBL361530 | AS-69959 | 2-(2-methoxyethoxy)ethyl tosylate | m-

Specifications & Purity

≥95%

Biochemical and Physiological Mechanisms

m-PEG2-Tos is an uncleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs).

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%

Names and Identifiers

• Pubchem Sid: 508811247
• Canonical Smiles: CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOC
• IUPAC Name: 2-(2-methoxyethoxy)ethyl 4-methylbenzenesulfonate
• InChIKey: PBKGNJXLJQARIN-UHFFFAOYSA-N
• INCHI: 1S/C12H18O5S/c1-11-3-5-12(6-4-11)18(13,14)17-10-9-16-8-7-15-2/h3-6H,7-10H2,1-2H3
• Isomeric SMILES: CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOC
• Molecular Weight: 274.34
• Reaxy-Rn: 2863313
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2863313&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Benzenesulfonic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Benzenesulfonic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Benzenesulfonate esters
• Alternative Parents: p-Methylbenzenesulfonates Tosyl compounds Benzenesulfonyl compounds Arylsulfonic acids and derivatives Organosulfonic acid esters Sulfonyls Dialkyl ethers Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Benzenesulfonate ester - P-methylbenzenesulfonate - Tosyl compound - Arylsulfonic acid or derivatives - Benzenesulfonyl group - Toluene - Organosulfonic acid ester - Sulfonyl - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Dialkyl ether - Ether - Organic oxygen compound - Organosulfur compound - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as benzenesulfonate esters. These are arenesulfonate esters that result from the formal condensation of the hydroxy group of an alcohol, enol, phenol or heteroarenol with benzenesulfonic acid.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Solubility (25°C) In vitro
• Flash Point(°C): 191 °C
• Molecular Weight: 274.340 g/mol
• XLogP3: 1.100
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 8
• Exact Mass: 274.087 Da
• Monoisotopic Mass: 274.087 Da
• Topological Polar Surface Area: 70.200 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 301.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1