Mancozeb - Moligand™, ≥80% , CAS No.8018-01-7

CAS: 8018-01-7 Cat. No.: M649002 Formula: C₄H₆MnN₂S₄・C₄H₆N₂S₄Zn Molecular Weight: 541.08 EC Number: 616-995-5 PubChem CID: 13307026

GRADE & PURITY Moligand™, ≥80%

Synonyms

MANCOZEB | Mancozeb, PESTANAL(R), analytical standard | 4-?(2-?chlorophenyl)?-?3-?[3-?[4-?(2-?chlorophenyl)?benzo[f]?quinolin-?3(4H)?-?ylidene]?-?1-?propen-?1-?yl]?-Benzo[f]?quinolinium? perchlorate (1:1) | Manganese Zinc ethylenebis(dithiocarbamate) | MF

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Biological Activity

Mancozeb is a widely used fungicide that is effective against fungal diseases in most cereals, vegetables, fruits and ornamental plants. In addition, Mancozeb can cause liver damage in mice by activating the Keap1/Nrf2 signaling pathway. Mancozeb upregulates lactate dehydrogenase and cytochrome c to alter cell metabolism and induce cell death. Mancozeb has reproductive toxicity and can induce apoptosis in ovarian cells.

Specifications

Synonyms

MANCOZEB | Mancozeb, PESTANAL(R), analytical standard | 4-?(2-?chlorophenyl)?-?3-?[3-?[4-?(2-?chlorophenyl)?benzo[f]?quinolin-?3(4H)?-?ylidene]?-?1-?propen-?1-?yl]?-Benzo[f]?quinolinium? perchlorate (1:1) | Manganese Zinc ethylenebis(dithiocarbamate) | MF

Specifications & Purity

Moligand™, ≥80%

Biochemical and Physiological Mechanisms

Mancozeb is an ethylene-bis-dithiocarbamate fungicide.

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Purity

≥80%

Names and Identifiers

• Canonical Smiles: C(CNC(=S)[S-])NC(=S)[S-].C(CNC(=S)[S-])NC(=S)[S-].[Mn+2].[Zn+2]
• IUPAC Name: zinc;manganese(2+);N-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate
• InChIKey: CHNQZRKUZPNOOH-UHFFFAOYSA-J
• INCHI: 1S/2C4H8N2S4.Mn.Zn/c2*7-3(8)5-1-2-6-4(9)10;;/h2*1-2H2,(H2,5,7,8)(H2,6,9,10);;/q;;2*+2/p-4
• Isomeric SMILES: C(CNC(=S)[S-])NC(=S)[S-].C(CNC(=S)[S-])NC(=S)[S-].[Mn+2].[Zn+2]
• PubChem CID: 13307026
• Molecular Weight: 541.08

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Dithiocarbamic acids and derivatives
      • Subclass Dithiocarbamic acid esters

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Dithiocarbamic acids and derivatives
• Subclass: Dithiocarbamic acid esters
• Intermediate Tree Nodes: Not available
• Direct Parent: Ethylene bisdithiocarbamates
• Alternative Parents: Metallobisdithiocarbamates Organic transition metal salts Organosulfur compounds Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives
• Molecular Framework: Not available
• Substituents: Ethylene bisdithiocarbamate - Metallobisdithiocarbamate - Organic transition metal salt - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organic salt - Organosulfur compound - Organonitrogen compound - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as ethylene bisdithiocarbamates. These are dithiocarbamic acids (or derivatives) resulting from the formal addition of a molecule of carbon disulfide to each amino group of ethylenediamine. In addition, compounds containing a 1,2-ethanediyl carbamodithioate moiety are also members of this class.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: H2O : 1 mg/mL (1.51 mM; ultrasonic and warming and heat to 80°C) DMSO : 1 mg/mL (1.51 mM; Need ultrasonic)

References

1. Zhigang Liu, Yi Wang, Rong Deng, Liyuan Yang, Shihua Yu, Shuping Xu, Weiqing Xu.  (2016)  Fe3O4@Graphene Oxide@Ag Particles for Surface Magnet Solid-Phase Extraction Surface-Enhanced Raman Scattering (SMSPE-SERS): From Sample Pretreatment to Detection All-in-One.  ACS Applied Materials & Interfaces,      [PMID:27191584] [10.1021/acsami.6b02944]