≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Masoprocol (meso-Nordihydroguaiaretic acid) is an orally active lipoxygenase (LOX) inhibitor, a compound isolated from Larrea tridentata with anticancer and antihyperglycemic activity. Masoprocol is used for the treatment of type 2 diabetes. Masoprocol is used in the treatment of type 2 diabetes.
| ALogP | 4.3 |
|---|
| Canonical Smiles | CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O |
|---|---|
| IUPAC Name | 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol |
| InChIKey | HCZKYJDFEPMADG-TXEJJXNPSA-N |
| INCHI | 1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3/t11-,12+ |
| Isomeric SMILES | C[C@H](CC1=CC(=C(C=C1)O)O)[C@@H](C)CC2=CC(=C(C=C2)O)O |
| Alternate CAS | 27686-84-6,500-38-9 |
| MeSH Entry Terms | (R*,S*)-4,4'-(2,3-Dimethylbutane-1,4-diyl)bispyrocatechol;Acid, meso-Nordihydroguaiaretic;Actinex;Dihydronorguaiaretic Acid;Masoprocol;meso Nordihydroguaiaretic Acid;meso-Nordihydroguaiaretic Acid;Nordihydroguaiaretic Acid;Nordihydroguaiaretic Acid, (R*,S |
| Molecular Weight | 302.36 |
| Reaxy-Rn | 9803564 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9803564&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lignans, neolignans and related compounds |
| Class | Dibenzylbutane lignans |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Dibenzylbutane lignans |
| Alternative Parents | Phenylpropanes Catechols 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Organooxygen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Dibenzylbutane lignan skeleton - Phenylpropane - Catechol - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Benzenoid - Monocyclic benzene moiety - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as dibenzylbutane lignans. These are lignan compounds containing a 2,3-dibenzylbutane moiety. |
| External Descriptors | Lignans |
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| Solubility | DMSO : ≥ 100 mg/mL (330.73 mM) |
|---|---|
| Molecular Weight | 302.400 g/mol |
| XLogP3 | 4.300 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 5 |
| Exact Mass | 302.152 Da |
| Monoisotopic Mass | 302.152 Da |
| Topological Polar Surface Area | 80.900 Ų |
| Heavy Atom Count | 22 |
| Formal Charge | 0 |
| Complexity | 303.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
H2518318