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Why this grade
Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
MFZ 10-7 is a highly potent and selective mGluR5 NAM (negative allosteric modulator), with a K i of 0.67 nM for rat mGluR5
In Vitro
MFZ 10-7 has approximately 1150- and 3000-fold lower affinity for MAO-B (monoamine oxidase-B enzyme) and TXA2 (thromboxane A2 receptor), respectively, compared to mGluR5. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MFZ 10-7 can lower oral sucrose self-administration rate but has no effect on total sucrose intake . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:rat mGluR5 0.67 nM (Ki)
Specifications
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
MFZ 10-7 is a highly potent and selective mGluR5 NAM (negative allosteric modulator), with a K i of 0.67 nM for rat mGluR5.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
ANTAGONIST
Purity
≥98%
Names and Identifiers
| Molecular Weight | 236.24 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 G2517425 | Certificate of Analysis | Feb 08, 2025 | M650237 |
| G2517426 | Certificate of Analysis | Feb 08, 2025 | M650237 |
| G2517427 | Certificate of Analysis | Feb 08, 2025 | M650237 |
| G2517428 | Certificate of Analysis | Feb 08, 2025 | M650237 |
| G2517429 | Certificate of Analysis | Feb 08, 2025 | M650237 |
| G2517430 | Certificate of Analysis | Feb 08, 2025 | M650237 |
| G2517431 | Certificate of Analysis | Feb 08, 2025 | M650237 |
| G2517432 | Certificate of Analysis | Feb 08, 2025 | M650237 |
| G2517433 | Certificate of Analysis | Feb 08, 2025 | M650237 |
Chemical and Physical Properties
| Solubility | DMSO : 17.86 mg/mL (75.60 mM; ultrasonic and warming and heat to 60°C) |
|---|
Solution Calculators
Reviews
Customer Reviews
Frequently Asked Questions
What is the purity of this product?
This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
What is Moligand??
Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 1224431-15-5, the molecular formula is C15H9FN2, and the molecular weight is 236.24 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
Need help choosing the grade?
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →Related Products
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