MOPS - ≥99.5%(T) , CAS No.1132-61-2

CAS: 1132-61-2 Cat. No.: M105135 Molecular Weight: 209.26 Beilstein Registry Number: 1106776 EC Number: 214-478-5
AVAILABLE TO ORDER
GRADE & PURITY ≥99.5%(T)
Synonyms
4-Morpholinepropanesulfonic acid | BBL010801 | MOPS | NCGC00255922-01 | Q4030654 | 3-Morpholinopropane-1-sulfonic acid | 3-(morpholin-4-yl)propane-1-sulfonic acid (MOPS) | MFCD11100867 | MOPS, BioUltra, for molecular biology, >=99.5% (T) | MOPS, BioXtra,
Storage
Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5g
M105135-5g
≥10
$9.90
25g
M105135-25g
2
$28.90
100g
M105135-100g
3
$63.90
500g
M105135-500g
3
$213.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥99.5%(T) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 106 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

useful pH range 6.5 - 7.9 pKa (25 °C) 7.2 3-(N-Morpholino)propane sulfonic acid (MOPS) is an N-substituted amino sulfonic acid with a morpholinic ring. MOPS is capable of buffering within a pH range of 6.5-7.9. MOPS is widely used in biological and biochemical studies due to its inert properties.It does not interact with any metal ions in solutions and has significant metal-buffer stability especially with copper (Cu), nickel (Ni), manganese (Mn), zinc (Zn), cobalt (Co) ions. MOPS buffer maintains the pH of the mammalian cell culture medium. MOPS functions to maintain pH in denaturing gel electrophoresis of RNA. MOPS can modify lipid interactions and influence the thickness and barrier properties of membranes. MOPS interacts with bovine serum albumin and stabilizes the protein. Hydrogen peroxide oxidizes MOPS slowly to N-oxide form
Good's buffer component for biological research Satisfactory for electron transport studies and phosphorylation in chloroplast lamella preparations; non-toxic buffering system for the extensive growth of Streptomyces clavuligerus and cephalosporin production, in a chemically defined medium; electrolyte system component for the IEF of 2-D gel electrophoresis

Specifications

Synonyms
4-Morpholinepropanesulfonic acid | BBL010801 | MOPS | NCGC00255922-01 | Q4030654 | 3-Morpholinopropane-1-sulfonic acid | 3-(morpholin-4-yl)propane-1-sulfonic acid (MOPS) | MFCD11100867 | MOPS, BioUltra, for molecular biology, >=99.5% (T) | MOPS, BioXtra,
Specifications & Purity
≥99.5%(T)
Storage
Room temperature
Shipped In
Normal
Purity
≥99.5%(T)
Names and Identifiers
Pubchem Sid504754576
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504754576
Canonical SmilesC1COCCN1CCCS(=O)(=O)O
IUPAC Name3-morpholin-4-ylpropane-1-sulfonic acid
InChIKeyDVLFYONBTKHTER-UHFFFAOYSA-N
INCHI1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)
Isomeric SMILES C1COCCN1CCCS(=O)(=O)O
WGK Germany 1
RTECS QE9104530
Molecular Weight 209.26
Beilstein 1106776
Reaxy-Rn 1106776
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1106776&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassOxazinanes
SubclassMorpholines
Intermediate Tree Nodes Not available
Direct ParentMorpholines
Alternative Parents Sulfonyls  Organosulfonic acids  Alkanesulfonic acids  Trialkylamines  Oxacyclic compounds  Dialkyl ethers  Azacyclic compounds  Organopnictogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAliphatic heteromonocyclic compounds
Substituents Morpholine - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Organosulfonic acid - Sulfonyl - Alkanesulfonic acid - Tertiary amine - Tertiary aliphatic amine - Dialkyl ether - Ether - Oxacycle - Azacycle - Organopnictogen compound - Organic oxygen compound - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Organic oxide - Hydrocarbon derivative - Amine - Aliphatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as morpholines. These are organic compounds containing a morpholine moiety, which consists of a six-member aliphatic saturated ring with the formula C4H9NO, where the oxygen and nitrogen atoms lie at positions 1 and 4, respectively.
External Descriptors an aliphatic sulfonate
3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

59 results found

Lot NumberCertificate TypeDateItem
H2202541Certificate of AnalysisMay 11, 2026 M105135
A2615416Certificate of AnalysisJan 05, 2026 M105135
A2615415Certificate of AnalysisJan 05, 2026 M105135
A2615414Certificate of AnalysisJan 05, 2026 M105135
A2615413Certificate of AnalysisJan 05, 2026 M105135
A2615402Certificate of AnalysisJan 05, 2026 M105135
K2528495Certificate of AnalysisOct 22, 2025 M105135
J2530643Certificate of AnalysisOct 22, 2025 M105135
J2530641Certificate of AnalysisOct 22, 2025 M105135
H2529530Certificate of AnalysisAug 22, 2025 M105135
H2529297Certificate of AnalysisAug 22, 2025 M105135
H2529529Certificate of AnalysisAug 22, 2025 M105135
H2529531Certificate of AnalysisAug 22, 2025 M105135
D2530206Certificate of AnalysisApr 24, 2025 M105135
D2530207Certificate of AnalysisApr 24, 2025 M105135
D2530208Certificate of AnalysisApr 24, 2025 M105135
L2413549Certificate of AnalysisDec 02, 2024 M105135
D2523154Certificate of AnalysisDec 02, 2024 M105135
L2413547Certificate of AnalysisDec 02, 2024 M105135
L2413548Certificate of AnalysisDec 02, 2024 M105135
A2104161Certificate of AnalysisOct 12, 2024 M105135
J2416574Certificate of AnalysisOct 10, 2024 M105135
H2407236Certificate of AnalysisJul 26, 2024 M105135
H2406632Certificate of AnalysisJul 26, 2024 M105135
H2406631Certificate of AnalysisJul 26, 2024 M105135
H2406630Certificate of AnalysisJul 26, 2024 M105135
H2408598Certificate of AnalysisJul 26, 2024 M105135
F2417225Certificate of AnalysisJun 07, 2024 M105135
F2417224Certificate of AnalysisJun 07, 2024 M105135
F2417223Certificate of AnalysisJun 07, 2024 M105135
E2416296Certificate of AnalysisMay 10, 2024 M105135
E2416305Certificate of AnalysisMay 10, 2024 M105135
E2416298Certificate of AnalysisMay 10, 2024 M105135
E2416304Certificate of AnalysisMay 10, 2024 M105135
E2410077Certificate of AnalysisMar 15, 2024 M105135
D2402347Certificate of AnalysisMar 15, 2024 M105135
D2402348Certificate of AnalysisMar 15, 2024 M105135
A2415422Certificate of AnalysisJan 04, 2024 M105135
E2410078Certificate of AnalysisJan 04, 2024 M105135
A2415421Certificate of AnalysisJan 04, 2024 M105135
F2315277Certificate of AnalysisMay 10, 2023 M105135
A2305411Certificate of AnalysisDec 01, 2022 M105135
A2305409Certificate of AnalysisDec 01, 2022 M105135
A2305412Certificate of AnalysisDec 01, 2022 M105135
A2305413Certificate of AnalysisDec 01, 2022 M105135
A2305416Certificate of AnalysisDec 01, 2022 M105135
A2305418Certificate of AnalysisDec 01, 2022 M105135
A2305368Certificate of AnalysisDec 01, 2022 M105135
A2305367Certificate of AnalysisDec 01, 2022 M105135
K2217923Certificate of AnalysisOct 09, 2022 M105135
B2301257Certificate of AnalysisJul 16, 2022 M105135
H2202505Certificate of AnalysisJul 16, 2022 M105135
H2202504Certificate of AnalysisJul 16, 2022 M105135
H2202503Certificate of AnalysisJul 16, 2022 M105135
G2214030Certificate of AnalysisJul 16, 2022 M105135
B2223487Certificate of AnalysisJan 18, 2022 M105135
B2223506Certificate of AnalysisJan 18, 2022 M105135
B2223507Certificate of AnalysisJan 18, 2022 M105135
B2223533Certificate of AnalysisJan 18, 2022 M105135

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Chemical and Physical Properties
SolubilitySoluble in water.
Flash Point(°F)116°C
Flash Point(°C)116°C
Melt Point(°C)277-282°C
Molecular Weight209.270 g/mol
XLogP3-3.100
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass209.072 Da
Monoisotopic Mass209.072 Da
Topological Polar Surface Area75.200 Ų
Heavy Atom Count13
Formal Charge0
Complexity227.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Nucleic Acid Electrophoresis Workflow—5 Main Steps
Buffer exchange of a sample using a dialysis bag
Standard Operating Procedure (SOP) for Bis-Tris Polyacrylamide Gel Electrophoresis (SDS-PAGE)
Common Protectants and Formulations for Protein Storage
Good’s buffers
A Review of Ten Commonly Used Techniques for Detection, Quantification, and Interaction Analysis in Nucleic Acid Research
How Organic Acids “Stabilize a System”: Selection Logic via the pH Window, Salt Forms, and Metal-Ion Management (with a navigation guide to Tables A–E)
Fluconazole: Physicochemical Properties, Mechanism of Action, and Key Points for Clinical and Research Applications
Phytase: Enzymological Properties, Mechanism of Action, and Applications in Feed and Food
Why Do So Many Molecules Incorporate an “Oxadiazole Ring”? A Stability-Oriented Design Guide from Structural Effects to Application Storylines (with Product Navigation Tables 1–3)
Functional Properties, Application Scenarios, and Manufacturing Processes of Maltotetraose (G4): A Review
Structural Characteristics, Operational Methods, and Separation Applications of Dextran Gels
Citations of This Product
References
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75. Jiangxiong Zhu, Hao Yin, Yang Wang, Lumei Wang, Xueqing Geng, Yun Deng.  (2024)  Conformational change-based fluorometric aptasensor for sensitive cadmium(II) detection in fruits and vegetables.  Analytical Methods,      [PMID:39143932] [10.1039/D4AY01333F]
76. Chengwei Li, Yanting Zhang, Yunsong Zheng, Chongwen Shi, Yuxi Lu, Yaoqiang Zhang, Songhu Yuan.  (2024)  Contaminant transformation during sediment oxygenation: Temporal variation of oxidation mechanisms mediated by hydroxyl radicals and aerobic microbes.  SCIENCE OF THE TOTAL ENVIRONMENT,      [PMID:38340822] [10.1016/j.scitotenv.2024.170855]
77. Fang Liu, Yongcheng Chen, Yue Huang, Qiao Jin.  (2024)  Copper-Polyphenol Nanocomplexes with Peroxidase-Like Activity for Enhanced Fungal Eradication.  ChemCatChem,      [PMID:] [10.1002/cctc.202401221]
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79. Xin Wang, Shengyan Pu, Jiaqi Ding, Jing Chen, Peng Liao, Delai Zhong, Daniel C. W. Tsang, John C. Crittenden, Linling Wang.  (2024)  Enhanced Arsenate Immobilization by Kaolinite via Heterogeneous Pathways during Ferrous Iron Oxidation.  ENVIRONMENTAL SCIENCE & TECHNOLOGY,      [PMID:38934384] [10.1021/acs.est.4c01976]
80. Yikai Chen, Binggang Ye, Mengling Ning, Meng Li, Yixuan Pu, Zhiming Liu, Huiqing Zhong, Chaofan Hu, Zhouyi Guo.  (2024)  Food-borne bacteria analysis using a diatomite bioinspired SERS platform.  Journal of Materials Chemistry B,  12  (24): (5974-5981).  [PMID:38809058] [10.1039/D4TB00488D]
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88. Xiaocui Lai, Wenkai Cao, Ganggang Zhang, Edison Huixiang Ang, Liu Su, Cong Liu, Weihua He, Weihua Lai, Shengliang Deng.  (2024)  Traffic signal-inspired fluorescence lateral flow immunoassay utilizing self-assembled AIENP@Ni/EC for simultaneous multi-pesticide residue detection.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.157565]
89. Ying Liu, Miao Wang, Guang-Xiong Zhou.  (2025)  Activity of 6-methoxydihydrosanguinarine from Hylomecon japonica against wild-type and fluconazole-resistant Candida albicans biofilms.  JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,      [PMID:40720099] [10.1080/10286020.2025.2532041]
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98. Kang Shaoyang, Ding Sheng, Lyu Donghao, Gao Rui, Peng Sirui, Liu Jing, Zhang Chuangnian, Feng Zujian, Huang Pingsheng, Kong Deling, Wang Weiwei.  (2025)  A Microgel-Stabilized, Light-Controlled Artificial Energy Supply Module for Efficient Biosynthesis.  Regenerative Biomaterials,      [PMID:41669165] [10.1093/rb/rbaf106]
99. Hongling Bu, Hanjie Chen, Chengshuai Liu, Hui Tong, Yanfu Wei, Meiqing Chen, Ziming Xu, Jianbo Chen, Peng Yuan.  (2025)  Clay Mineral Structure Dictates Arsenic(III) Oxidative Fate: Mechanistic Insights from Contrasting 1:1 and 2:1 Phyllosilicates.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:41349308] [10.1016/j.jhazmat.2025.140665]
100. Huang Junyun, Liu Boying, Yuan Sijia, Zhou Haiyun, Bao Jian, Tu Yong, Wang Zunyao, Wang Weixia.  (2025)  The pH-Dependent Toxic Effects of Benzophenone-3 on Aquatic Organisms.  BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY,  116  (1): (9).  [PMID:41400706] [10.1007/s00128-025-04167-x]
101. Yunqi Xiao, Shanyu Zhang, Xinmeng Gao, Tian Li, Hanhan Zhang, Panke Zhang, Shuo Huang.  (2026)  Nanopore profiling and structure determination of oligosaccharides by fragmentation.  Science Advances,  12  (1):   [PMID:41477834] [10.1126/sciadv.aea8462]
102. Xiong Liu, Guangxia Feng, Yuan Ping, Zhiping Zhang, Li Kong.  (2026)  Inhaled engineered apoptotic neutrophil-derived nanovesicles enhance macrophage efferocytosis for attenuating lung inflammation.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2026.173072]
103. Bowen Sun, Ying Wang, Jaslyn Ru Ting Chen, Manli Guo, Emily Xi Tan, Lam Bang Thanh Nguyen, Wanzong Wang, Hao Feng, In Yee Phang, Yan Lv, Jianhua Li, Xing Yi Ling, Qi-Zhi Zhong.  (2026)  Surface engineering of SERS nanocomposites via metal–phenolic networks for stable sensing.  COMPOSITES COMMUNICATIONS,      [PMID:] [10.1016/j.coco.2026.102753]
104. Yahui Xie, Yun Liu, Haibo Zhao, Xuemin Kang, Haiteng Tao, Bin Yu, Bo Cui.  (2026)  Gelatin/starch hydrogel tissue adhesive loaded with EGCG-Zr complex with antibacterial, antioxidant, and immunomodulatory properties for advanced wound healing.  Biomaterials Advances,      [PMID:41690128] [10.1016/j.bioadv.2026.214769]
105. Jingwen Xu, Xu Hu, Zongyan Li, Junhan Li, Zhida Gao, Zhi-Yong Wu, Yan-Yan Song.  (2026)  Development of a Paper-Based SERS Platform for On-Site Separation and Detection of Mercury Species in Aqueous Environments.  ANALYTICAL CHEMISTRY,      [PMID:41666277] [10.1021/acs.analchem.5c06628]
106. Wanlei Ren, Junqi Zhao, Xujuan Lv, Sha Qiu, Yujia Ren, Xuxin Yan, Shuai Qin, Daoqing Fan, Juan Wang, Xueji Zhang.  (2026)  Colorimetric sensor arrays for the analysis of active ingredients in licorice based on the efficient catalysis of oxidase-like manganese-nanozymes.  TALANTA,      [PMID:] [10.1016/j.talanta.2026.129570]
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