n-Butyllithium solution - 2.5 M in hexanes(23% solution) , CAS No.109-72-8

CAS: 109-72-8 Cat. No.: B118688 Formula: C4H9Li Molecular Weight: 64.06 Beilstein Registry Number: 1209227 EC Number: 203-698-7
AVAILABLE TO ORDER
GRADE & PURITY 2.5 M in hexanes(23% solution)
Synonyms
LiBu | n-BuLi | N-butyllithium | butyl lithium | n-BuLi | Butyl lithium | Butyllithium solution | Lithium-1-butanide | n-Butyllithium | Butyllithium
Storage
Store at 2-8°C,Argon charged
Shipped In
Wet ice,FedEx DG Service
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Size
Germany (EU)
USA*
Price
Qty
100ml
B118688-100ml
—
2 In stock
€64.99
500ml
B118688-500ml
—
3 In stock
€182.14
Enter a quantity for the sizes you want to add.
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Why this grade

2.5 M in hexanes(23% solution) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Argon charged Ships Wet ice,FedEx DG Service Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 123 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

n-Butyllithium (n-BuLi) is an organolithium reagent widely used as a strong base (superbase) in organic synthesis for the preparation of various chemical intermediates. It is also used as a reagent for lithium-halogen exchange and lithium-metal transmetalation reactions. n-BuLi is capable of lithiating carbon acids.


Application:
n-Butyllithium can be used as:      
A polymerization initiator to synthesize polystyrenes by anionic polymerization of styrene.      
A strong base in the diastereoselective alkylation reactions.
A reagent to synthesize 2-benzoylpyrroles by reacting benzaldehydes with di(1H-pyrrol-1-yl)zirconium(IV) chloride complex.

Specifications

Synonyms
LiBu | n-BuLi | N-butyllithium | butyl lithium | n-BuLi | Butyl lithium | Butyllithium solution | Lithium-1-butanide | n-Butyllithium | Butyllithium
Specifications & Purity
2.5 M in hexanes(23% solution)
Storage
Store at 2-8°C,Argon charged
Shipped In
Wet ice,FedEx DG Service
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
Isomeric SMILES
[Li+].CCC[CH2-]
WGK Germany
2
UN Number
3394
Packing Group
I
Molecular Weight
64.06
Beilstein
1209227
Reaxy-Rn
1209227
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1209227&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

27 results found

Lot NumberCertificate TypeDateItem
E2625267Certificate of AnalysisMay 15, 2026 B118688
E2625278Certificate of AnalysisMay 15, 2026 B118688
L2526033Certificate of AnalysisDec 19, 2025 B118688
L2526029Certificate of AnalysisDec 19, 2025 B118688
J2530164Certificate of AnalysisOct 27, 2025 B118688
J2530163Certificate of AnalysisOct 27, 2025 B118688
J2528300Certificate of AnalysisOct 20, 2025 B118688
G2501334Certificate of AnalysisMay 26, 2025 B118688
G2501333Certificate of AnalysisMay 26, 2025 B118688
D2521139Certificate of AnalysisApr 08, 2025 B118688
D2521140Certificate of AnalysisApr 08, 2025 B118688
L2425254Certificate of AnalysisDec 09, 2024 B118688
L2425252Certificate of AnalysisDec 09, 2024 B118688
H2426398Certificate of AnalysisAug 14, 2024 B118688
H2426399Certificate of AnalysisAug 14, 2024 B118688
A2419173Certificate of AnalysisJan 05, 2024 B118688
G2315211Certificate of AnalysisJul 05, 2023 B118688
G2315240Certificate of AnalysisJul 05, 2023 B118688
C2130173Certificate of AnalysisJan 11, 2023 B118688
K2223129Certificate of AnalysisNov 15, 2022 B118688
K2223130Certificate of AnalysisNov 15, 2022 B118688
I2205515Certificate of AnalysisAug 23, 2022 B118688
I2203087Certificate of AnalysisAug 23, 2022 B118688
F2223168Certificate of AnalysisJun 14, 2022 B118688
F2223169Certificate of AnalysisJun 14, 2022 B118688
C2203028Certificate of AnalysisFeb 18, 2022 B118688
C2203005Certificate of AnalysisFeb 18, 2022 B118688
Chemical and Physical Properties
SolubilityMiscible with diethyl ether and cyclohexane.
SensitivityAir & Moisture Sensitive;Heat sensitive
Flash Point(°F)10 °F
Flash Point(°C)-21℃
Boil Point(°C)80°C
Melt Point(°C)-95 °C
Documents & Articles
Pinacolborane
OSF/ASF Dual-Channel Toolbox: Divergent Reactions of Four-Membered Ring Sulfonyl Fluorides, Condition “Knobs,” and Selection Navigation
How to Make Organolithium Reactions Reproducible: Lock Down the Effective Equivalents, Aggregation State, and the Addition/Temperature-Control Window
Experimental Selection of SEM-Cl: From O/N-SEM Protection and Directed Functionalization of N-Heterocycles to the Introduction of Protected C1 Fragments
Experimental Selection Logic for C-C Bond Construction: Understanding Fragment Coupling, Carbonyl Chain Extension, Olefination, and Late-Stage Bond-Forming Pathways by Bond-Forming Task
From Nucleophilic to Electrophilic BCB Synthetic Equivalents: Hypervalent-Iodine-Mediated Umpolung Design
One-Pot Arylation of the Piperidine α-C–H Bond: From Directed Lithiation and Li→Zn Transmetalation to Negishi Coupling
Where Does the Selectivity in Piperidine C–H Functionalization Come From? — Nitrogen Effects, Chair Conformations, and Four Classes of Key Intermediates
3,3-Spiro-α-Proline Building Blocks: Structural Features, Complementary Synthetic Routes, and Multigram-Scale Preparation
Direct Construction of Methylsulfonyl-Containing Heterocycles: Synthesis and Applications of Prefunctionalized Three-Carbon Vinamidinium Salts
Regioselective Deprotonative Metalation of Pyridines: C–H Acidity, Coordination Effects, and Metal Systems
Citations of This Product
Solution Calculators
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