10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Nalidixic acid (NSC-82174) is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
In vitro
In vivo
Cell Data
cell lines：
Concentrations：
Incubation Time：
Powder Purity:
| ALogP | 1.4 |
|---|
| Isomeric SMILES | CCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)O |
|---|---|
| WGK Germany | 2 |
| RTECS | QN2885000 |
| UN Number | 3249 |
| Packing Group | II |
| Molecular Weight | 232.24 |
| Beilstein | 750515 |
| Reaxy-Rn | 750515 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=750515&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Solubility | Solubility (25°C) In vitro DMSO: 47 mg/mL (199.79 mM); Water: 47 mg/mL (199.79 mM); Ethanol: Insoluble; |
|---|---|
| Melt Point(°C) | 229-230°C |
| 1. Xiaoyi Pu, Xin Wang, Youping Liu, Xin Di. (2023) A novel deep eutectic solvent-based ultrasound-assisted dispersive liquid–liquid microextraction coupled with high-performance liquid chromatography for the determination of quinolones in environmental water samples. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2023.109374] |
| 2. Yuliya E. Tyutereva, Olga A. Snytnikova, Roman G. Fedunov, Vadim V. Yanshole, Victor F. Plyusnin, Jing Xu, Ivan P. Pozdnyakov. (2023) Direct UV photodegradation of nalidixic acid in aqueous solutions: A mechanistic study. CHEMOSPHERE, [PMID:37201608] [10.1016/j.chemosphere.2023.138952] |
| 3. Okon Johnson Esua, Da-Wen Sun, Clement Kehinde Ajani, Jun-Hu Cheng, Kevin M. Keener. (2022) Modelling of inactivation kinetics of Escherichia coli and Listeria monocytogenes on grass carp treated by combining ultrasound with plasma functionalized buffer. ULTRASONICS SONOCHEMISTRY, [PMID:35830785] [10.1016/j.ultsonch.2022.106086] |
| 4. Shang Wu, Yang Yang, Tingwei Wang, Jiadi Sun, Yinzhi Zhang, Jian Ji, Xiulan Sun. (2021) Effects of acid, alkaline, cold, and heat environmental stresses on the antibiotic resistance of the Salmonella enterica serovar Typhimurium. FOOD RESEARCH INTERNATIONAL, [PMID:34053552] [10.1016/j.foodres.2021.110359] |
| 5. Shiqing Zhou, Ling Li, Yangtao Wu, Shumin Zhu, Ningyuan Zhu, Lingjun Bu, Dionysios D. Dionysiou. (2020) UV365 induced elimination of contaminants of emerging concern in the presence of residual nitrite: Roles of reactive nitrogen species. WATER RESEARCH, [PMID:32375111] [10.1016/j.watres.2020.115829] |
| 6. Kang Yajing, Wang Yingying, Hou Bingbing, Wang Ruida, Ye Jiang, Zhu Xiaoyu, Wu Haizhen, Zhang Huizhan. (2019) AdpAlin, a Pleiotropic Transcriptional Regulator, Is Involved in the Cascade Regulation of Lincomycin Biosynthesis in Streptomyces lincolnensis. Frontiers in Microbiology, [PMID:31708899] [10.3389/fmicb.2019.02428] |
| 7. Sandip Mondal, Jianqiao Xu, Guosheng Chen, Siming Huang, Chuyu Huang, Li Yin, Gangfeng Ouyang. (2018) Solid-phase microextraction of antibiotics from fish muscle by using MIL-101(Cr)NH2-polyacrylonitrile fiber and their identification by liquid chromatography-tandem mass spectrometry. ANALYTICA CHIMICA ACTA, [PMID:30567665] [10.1016/j.aca.2018.09.060] |
| 8. Su Han Wang, Min Lin, Jing Liu, Jian Ping Wang, Ning Peng Wu. (2025) Discriminative determination of 15 fluoroquinolones in chicken muscle by Fe3O4@QepA based semi-homogeneous fluorescent array. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.113051] |
