β-Naphthoflavone - Moligand™, 10 mM in DMSO , CAS No.6051-87-2

CAS: 6051-87-2 Cat. No.: N1494885 Formula: C₁₉H₁₂O₂ Molecular Weight: 272.3 Beilstein Registry Number: 18991 EC Number: 227-958-4

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

β-Naphthoflavone is an exogenous aryl hydrocarbon receptor ( AHR ) ligand. β-Naphthoflavone can activate AHR to participate in various biological processes, including cell growth, differentiation, apoptosis , and metabolism. β-Naphthoflavone has antioxidant activity and can exert its antioxidant function by regulating the activity of antioxidant enzymes . β-Naphthoflavone is also a non-carcinogenic CYP1A inducer and can be used to treat aristolochic acid (AAI) induced renal injury.

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Names and Identifiers

• Isomeric SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC4=CC=CC=C43
• WGK Germany: 3
• RTECS: QL6200000
• Molecular Weight: 272.3
• Beilstein: 18991
• Reaxy-Rn: 18991
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=18991&ln=

Chemical and Physical Properties

• Melt Point(°C): 165 °C

References

1. Yingying Liang, Hailin Liu, Lin Wang, Jing Zhao, Shunyi Li, Li Yi, Sijing Jiang, Zhenghui Lu, Guimin Zhang.  (2024)  A new yeast-based bioreporter for simple, sensitive, and cost-effective detection of dioxin-like compounds.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2024.136730]

2. Wanglong Zhang, Yanjiao Zong, Ruize Sun, Zhenhong Xue, Wenhui Wan, Anran Ren, Yongchao Ma, Wenjing Tian, Renjun Wang.  (2025)  Characterization of the marine medaka AHRs and the comparison with those of Japanese medaka in response to dioxin and additional AHR ligands.  AQUATIC TOXICOLOGY,      [PMID:40107146] [10.1016/j.aquatox.2025.107323]

3. Anxiang Zhuang, Xu Zhao, Xiaoxue Lu, Shengyi Wang, Xi Zeng, Xiaoyu Li, Siquan Yu, Meiqi Xie, Yang Mei, Haibin Yuan, Xiangkun Meng.  (2025)  AhR/ARNT-mediated regulation of detoxification metabolism and enzyme genes in the red flour beetle, Tribolium castaneum.  PEST MANAGEMENT SCIENCE,      [PMID:41362244] [10.1002/ps.70435]

4. Lili Wu, Siyu Chen, Qiyuan Yang, Xing Li, Lingyan Liu, Shengjun Ji, Shuaiyuan Tang, Sihui Zhang, Yan Wang, Runzhi Chen, Zhikun Zhan.  (2026)  Cytochrome P450-Mediated Detoxification and NF-κB/NLRP3 Pathway-Driven Hepatotoxicity of Emodin: Multiomics and laboratory evidence.  CHEMICO-BIOLOGICAL INTERACTIONS,      [PMID:41579920] [10.1016/j.cbi.2026.111934]

Frequently Asked Questions

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 6051-87-2, the molecular formula is C19H12O2, and the molecular weight is 272.3 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.