Noladin ether - Moligand™, ≥98%, a solution in ethanol , Agonist of GPR55, CAS No.222723-55-9, Agonist of GPR55
Potent cannabinoid receptor agonist
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Potent cannabinoid receptor agonist
Noladin ether (2-Arachidonyl glycerol ether) is a stable analog of the endogenous cannabanoid 2-Arachidonylglycerol (2-AG) with selectivity for CB1 receptors. Noladin ether is a CB1 agonist. The Ki values for CB1 vs CB2 receptors are 21.2 nM and 3 mM, respectively. Noladin ether induces sedation and has modest antinociceptive activity in vivo, and reduces inter ocular pressure after administration in the eye.
2-Arachidonyl glycerol ether (2-AG ether) is supplied as a solution in ethanol. To change the solvent, simply evaporate the ethanol under a gentle stream of nitrogen and immediately add the solvent of choice. Solvents such as DMSO and dimethyl formamide purged with an inert gas can be used.
| CAS | 222723-55-9 |
|---|---|
| Concentration | ~10mg/mL in ethanol |
| Synonyms | Noladin | 2-AG ether | 6,7-DIHYDRO-5H-PYRINDINE | BCP04588 | PD020897 | BDBM50171296 | 2-O-(5Z,8Z,11Z,14Z)-eicosatetraenylglycerol | EINECS 208-606-9 | HY-110014 | 2-[((11Z,14Z)-Icosa-5,8,11,14-tetraenyl)oxy]-propane-1,3-diol | 2-[(5Z,8Z,11Z,14Z)-icosa-5, |
| Specifications & Purity | Moligand™, ≥98%, ~10mg/mL in ethanol |
| Storage | Desiccated,Store at -80°C |
| Shipped In | Dry ice packs + Cold packs |
| Product Description | Noladin ether (2-Arachidonyl glycerol ether) is a stable analog of the endogenous cannabanoid 2-Arachidonylglycerol (2-AG) with selectivity for CB1 receptors. Noladin ether is a CB1 agonist. The Ki values for CB1 vs CB2 receptors are 21.2 nM and 3 mM, respectively. Noladin ether induces sedation and has modest antinociceptive activity in vivo, and reduces inter ocular pressure after administration in the eye. |
| Solubility | Soluble in DMSO to 100 mM and in ethanol to 50 mM |
| PubChem CID | 6483057 |
| Molecular Formula | C23H40O3 |