Norcantharidin - ≥98% , CAS No.29745-04-8

CAS: 29745-04-8 Cat. No.: N159736 Formula: C8H8O4 Molecular Weight: 168.15 EC Number: 681-692-7
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
AKOS006276813 | 4,7-EPOXYISOBENZOFURAN-1,3-DIONE, HEXAHYDRO-, (3A.ALPHA.,4.BETA.,7.BETA.,7A.ALPHA.)- | CGA-110752 | Demethylcantharidin | ( inverted exclamation markA)-NCTD | Z1198158002 | HY-N2108 | NSC-59023 | UNII-8452E71EO7 | N0914 | (1S,2R,6S,7R)-4,1
Storage
Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
★
Size
Germany (EU)
USA*
Price
Qty
250mg
N159736-250mg
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2 In stock

€8.59

€12.93
Save €4.34 (33.56%)
1g
N159736-1g
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1 In stock

€19.00

€28.55
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5g
N159736-5g
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1 In stock

€72.80

€109.25
Save €36.45 (33.36%)
25g
N159736-25g
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1 In stock

€217.72

€327.05
Save €109.34 (33.43%)
Enter a quantity for the sizes you want to add.
🧪
Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 7 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Norcantharidin is a synthetic anticancer compound which is a dual inhibitor for c-Met and EGFR in human colon cancers.


Application:

exo-7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride acts as a potential antitumor agent. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.

Specifications

Synonyms
AKOS006276813 | 4,7-EPOXYISOBENZOFURAN-1,3-DIONE, HEXAHYDRO-, (3A.ALPHA.,4.BETA.,7.BETA.,7A.ALPHA.)- | CGA-110752 | Demethylcantharidin | ( inverted exclamation markA)-NCTD | Z1198158002 | HY-N2108 | NSC-59023 | UNII-8452E71EO7 | N0914 | (1S,2R,6S,7R)-4,1
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
Norcantharidin is a potential antitumor agent. Norcantharidin helps to block SK-N-SH neuroblastoma cell growth by stimulating autophagy and apoptosis.
Storage
Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%
Names and Identifiers
Pubchem Sid
Canonical Smiles
C1CC2C3C(C1O2)C(=O)OC3=O
IUPAC Name
(1R,2S,6R,7S)-4,10-dioxatricyclo[5.2.1.02,6]decane-3,5-dione
InChIKey
JAABVEXCGCXWRR-FBXFSONDSA-N
INCHI
1S/C8H8O4/c9-7-5-3-1-2-4(11-3)6(5)8(10)12-7/h3-6H,1-2H2/t3-,4+,5-,6+
Isomeric SMILES
C1C[C@H]2[C@H]3[C@@H]([C@@H]1O2)C(=O)OC3=O
Molecular Weight
168.15
Reaxy-Rn
162827
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=162827&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassFurofurans
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentFurofurans
Alternative Parents Dicarboxylic acids and derivatives  Oxolanes  Carboxylic acid anhydrides  Lactones  Oxacyclic compounds  Dialkyl ethers  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic heteropolycyclic compounds
Substituents Furofuran - Dicarboxylic acid or derivatives - Oxolane - Carboxylic acid anhydride - Lactone - Oxacycle - Ether - Dialkyl ether - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as furofurans. These are organic compounds containing a two furan rings fused to each other. Furan is a five-membered aromatic ring with four carbon atoms and one oxygen atom.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
PPP1CC Tchem Serine/threonine protein phosphatase PP1-gamma catalytic subunit (63 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Homo sapiens (32628 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DU-145 (51482 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HL-60 (67320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HT-29 (80576 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KB 3-1 (1143 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SW480 (6023 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A-431 (6446 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Colon cancer cell line (58 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H460 (60772 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A2780 (11979 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Jurkat (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDA-MB-231 (73002 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BT-549 (31254 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Serine-threonine protein phosphatase 2A regulatory subunit (96 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeDateItem
G2412497Certificate of AnalysisJul 26, 2024 N159736
G2412504Certificate of AnalysisJul 26, 2024 N159736
G2412486Certificate of AnalysisJul 23, 2024 N159736
G2412487Certificate of AnalysisJul 23, 2024 N159736
G2412488Certificate of AnalysisJul 23, 2024 N159736
G2412489Certificate of AnalysisJul 23, 2024 N159736
G2412490Certificate of AnalysisJul 23, 2024 N159736
G2412498Certificate of AnalysisJul 23, 2024 N159736
H2329816Certificate of AnalysisAug 17, 2023 N159736
H2329817Certificate of AnalysisAug 17, 2023 N159736
Chemical and Physical Properties
SolubilityHydrolyzes in water.
SensitivityMoisture sensitive
Melt Point(°C)111-117(℃)
Molecular Weight168.150 g/mol
XLogP3-0.100
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Exact Mass168.042 Da
Monoisotopic Mass168.042 Da
Topological Polar Surface Area52.600 Ų
Heavy Atom Count12
Formal Charge0
Complexity246.000
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
Solution Calculators
Reviews

Customer Reviews

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