NSC45586 - ≥98% , CAS No.6300-44-3

CAS: 6300-44-3 Cat. No.: N413106 Formula: C₂₀H₁₇N₆NaO₃ Molecular Weight: 412.38 PubChem CID: 135422008

GRADE & PURITY ≥98%

Synonyms

NSC45586 | sodium;5-[[4-[(2,4-diamino-5-methylphenyl)diazenyl]phenyl]diazenyl]-2-hydroxybenzoic acid | DTXSID40713364 | AKOS040759602 | sodium;(3Z)-3-[[4-[(2,4-diamino-5-methylphenyl)diazenyl]phenyl]hydrazinylidene]-6-oxocyclohexa-1,4-diene-1-carboxylic a

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Information

NSC45586 NSC45586 is an inhibitor of PHLPP (Pleckstrin homology domain and leucine-rich repeat protein phosphatase) , which is selective for PHLPP1 and PHLPP2.

Targets

PHLPP

Specifications

Synonyms

NSC45586 | sodium;5-[[4-[(2,4-diamino-5-methylphenyl)diazenyl]phenyl]diazenyl]-2-hydroxybenzoic acid | DTXSID40713364 | AKOS040759602 | sodium;(3Z)-3-[[4-[(2,4-diamino-5-methylphenyl)diazenyl]phenyl]hydrazinylidene]-6-oxocyclohexa-1,4-diene-1-carboxylic a

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

NSC45586 is an inhibitor of PHLPP (Pleckstrin homology domain and leucine-rich repeat protein phosphatase), which is selective for PHLPP1 and PHLPP2.

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 488202879
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488202879
• Canonical Smiles: CC1=CC(=C(C=C1N)N)N=NC2=CC=C(C=C2)N=NC3=CC(=C(C=C3)O)C(=O)O.[Na+]
• IUPAC Name: sodium;5-[[4-[(2,4-diamino-5-methylphenyl)diazenyl]phenyl]diazenyl]-2-hydroxybenzoic acid
• InChIKey: XPYXCDXPWJROPD-UHFFFAOYSA-N
• INCHI: 1S/C20H18N6O3.Na/c1-11-8-18(17(22)10-16(11)21)26-24-13-4-2-12(3-5-13)23-25-14-6-7-19(27)15(9-14)20(28)29;/h2-10,27H,21-22H2,1H3,(H,28,29);/q;+1
• Isomeric SMILES: CC1=CC(=C(C=C1N)N)N=NC2=CC=C(C=C2)N=NC3=CC(=C(C=C3)O)C(=O)O.[Na+]
• PubChem CID: 135422008
• Molecular Weight: 412.38

Chemical and Physical Properties

• Solubility: Solubility (25°C) In vitro DMSO: 82 mg/mL (198.84 mM); Water: Insoluble; Ethanol: Insoluble