Determine the necessary mass, volume, or concentration for preparing a solution.
NSC689857 - 10mM in DMSO , CAS No.241127-79-7
AVAILABLE TO ORDER
GRADE & PURITY 10mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
224,000+ research products · Triple ISO certified · COA & SDS available for every product · Same-day shipping on in-stock items
Why this grade
10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
NSC689857 is a potent EGFR and SCF SKP2 inhibitor with an IC 50 value of 36 μM for Skp2-Cks1. NSC689857 can inhibit p27 ubiquitylation (IC 50 =30 μM). NSC689857 has varied activity across cancer types, with more activity against leukemia cell lines than others
IC50& Target:IC 50 : 36 μM (Skp2-Cks1), 30 μM (p27 ubiquitylation)
Specifications
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
NSC689857 is a potent EGFR and SCF SKP2 inhibitor with an IC 50 value of 36 μM for Skp2-Cks1. NSC689857 can inhibit p27 ubiquitylation (IC 50 =30 μM). NSC689857 has varied activity across cancer types, with more activity against leukemia cell lines than o
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Names and Identifiers
| Isomeric SMILES | C1C2CC3CC1CC(C2)(C3)COC(=O)C4=CC=C(C=C4)NCC5=C(C=CC(=C5)O)O |
|---|---|
| PubChem CID | 391131 |
| Molecular Weight | 407.50 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
Reviews
Customer Reviews
Frequently Asked Questions
How should this product be stored?
Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 241127-79-7, the molecular formula is C25H29NO4, and the molecular weight is 407.50 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
Remind me later
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.