PDC31 - ≥99% , CAS No.634586-40-6

CAS: 634586-40-6 Cat. No.: P651839 Formula: C₄₅H₇₁N₁₃O₁₃ Molecular Weight: 1002.12

GRADE & PURITY ≥99%

Storage

Protected from light,Argon charged,Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

PDC31 (THG113.31; ILGHXDYK) is an allosteric and non-competitive inhibitor of FP Prostaglandin Receptor . PDC31 is the D-amino acid-based oligopeptide, is used for smooth muscle contractile agent. PDC31 decreases the strength and duration of uterine contractions in vivo, which can be used for research of preterm labor and primary dysmenorrhea (PD). PDC31 also enhances Ca 2+ -dependent large-conductance K + -channel in human myometrial cells

In Vitro

PDC31 (10 μM, 50 μM; ) stimulates the BK Ca channel in human myometrial smooth muscle cells, and enhances open state channel activity with average 4 and 6-fold by 10 and 50 μM, respectively. PDC31 (1 nM-10 μM; 20 min intervals) cumulatively inhibits spontaneous contractions in isolated pregnant human myometrium. PDC31 consists of ILGHXDYK, associated sequence is based on a transmembrane domain of the human PGF2a receptor. PDC31 has been shown to reduce the duration and strength of PGF2a-induced contractions in myometrial strip models and to delay delivery in animal models of preterm labor . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:FP Receptor ~30 nM (Ki) PGF 2α

Specifications

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

PDC31 (THG113.31; ILGHXDYK) is an allosteric and non-competitive inhibitor of FP Prostaglandin Receptor . PDC31 is the D-amino acid-based oligopeptide, is used for smooth muscle contractile agent. PDC31 decreases the strength and duration of uterine contr

Storage

Protected from light,Argon charged,Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥99%

Names and Identifiers

Molecular Weight

1002.12

Chemical and Physical Properties

• Solubility: H2O : 100 mg/mL (99.79 mM; Need ultrasonic)

Frequently Asked Questions

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?80 °C, protected from light, desiccated, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 634586-40-6, the molecular formula is C45H71N13O13, and the molecular weight is 1002.12 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.