PGS-IN-1 - Moligand™,≥99% , CAS No.102271-49-8

CAS: 102271-49-8 Cat. No.: P649115 Formula: C19H26O3 Molecular Weight: 302.41
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
Synonyms
KME-4 | (E)-3-(3,5-di-tert-butyl-4-hydroxybenzylidene)dihydrofuran-2(3H)-one
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
Germany (EU)
USA*
Price
Qty
1mg
P649115-1mg
Made to order · 8–12 wks
€25.95
5mg
P649115-5mg
Made to order · 8–12 wks
€78.01
25mg
P649115-25mg
Made to order · 8–12 wks
€234.20
100mg
P649115-100mg
Made to order · 8–12 wks
€702.78
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Moligand™,≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

PGS-IN-1 is a potent inhibitor of prostaglandin synthetase (PGS) with an IC 50 of 0.28 μM; also inhibits 5-lipoxygenase with an IC 50 of 1.05 μM.

In Vitro

The synthesized α-benzulidene-γ-butyrolactones are pure isomers (either cis or trans ). PGS-IN-1 is the trans isomer. PGS-IN-1 exhibits potent antiinflammatrory and PGS inhibitory activity (IC 50 =0.28 μM). PGS-IN-1 also shows potent inhibitory activity against 5-lipoxygenase (IC 50 =1.05 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:5-Lipoxygenase 1.05 μM (IC 50 )

Specifications

Synonyms
KME-4 | (E)-3-(3,5-di-tert-butyl-4-hydroxybenzylidene)dihydrofuran-2(3H)-one
Specifications & Purity
Moligand™,≥99%
Biochemical and Physiological Mechanisms
PGS-IN-1 is a potent inhibitor of prostaglandin synthetase (PGS) with an IC 50 of 0.28 μM; also inhibits 5-lipoxygenase with an IC 50 of 1.05 μM.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
INHIBITOR
Purity
≥99%
Names and Identifiers
Molecular Weight 302.41

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
H2626323Certificate of AnalysisMar 18, 2026 P649115
H2626438Certificate of AnalysisMar 18, 2026 P649115
H2626439Certificate of AnalysisMar 18, 2026 P649115
H2626440Certificate of AnalysisMar 18, 2026 P649115
Solution Calculators
Reviews

Customer Reviews

Frequently Asked Questions

What is the purity of this product?
This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
What is Moligand??
Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 102271-49-8, the molecular formula is C19H26O3, and the molecular weight is 302.41 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Moligand™ grade guide →

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.