≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Piromelatine (Neu-P11) is a melatonin MT1/MT2 receptor agonist, serotonin 5-HT1A/5-HT1D agonist, and serotonin 5-HT2B antagonist. Piromelatine (Neu-P11) possesses sleep promoting, analgesic, anti-neurodegenerative, anxiolytic and antidepressant potentials. Piromelatine (Neu-P11) also possesses pain-related P2X3, TRPV1, and Nav1.7 channel-inhibition capacities
| ALogP | 1.7 |
|---|
| Pubchem Sid | 528766775 |
|---|---|
| Canonical Smiles | COC1=CC2=C(C=C1)NC=C2CCNC(=O)C3=CC(=O)C=CO3 |
| IUPAC Name | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxopyran-2-carboxamide |
| InChIKey | PNTNBIHOAPJYDB-UHFFFAOYSA-N |
| INCHI | 1S/C17H16N2O4/c1-22-13-2-3-15-14(9-13)11(10-19-15)4-6-18-17(21)16-8-12(20)5-7-23-16/h2-3,5,7-10,19H,4,6H2,1H3,(H,18,21) |
| Isomeric SMILES | COC1=CC2=C(C=C1)NC=C2CCNC(=O)C3=CC(=O)C=CO3 |
| Alternate CAS | 946846-83-9 |
| PubChem CID | 24815904 |
| MeSH Entry Terms | N-(2-(5-methoxy-indol-3-yl)-ethyl)-4-oxo-4H-pyran-2-carboxamide;Neu-P11;piromelatine |
| Molecular Weight | 312.32 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Indoles and derivatives |
| Subclass | Indoles |
| Intermediate Tree Nodes | Not available |
| Direct Parent | 3-alkylindoles |
| Alternative Parents | Anisoles 2-heteroaryl carboxamides Pyranones and derivatives Alkyl aryl ethers Substituted pyrroles Heteroaromatic compounds Secondary carboxylic acid amides Cyclic ketones Oxacyclic compounds Azacyclic compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | 3-alkylindole - 2-heteroaryl carboxamide - Anisole - Phenol ether - Alkyl aryl ether - Pyranone - Pyran - Benzenoid - Substituted pyrrole - Heteroaromatic compound - Pyrrole - Carboxamide group - Cyclic ketone - Secondary carboxylic acid amide - Carboxylic acid derivative - Ether - Oxacycle - Azacycle - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as 3-alkylindoles. These are compounds containing an indole moiety that carries an alkyl chain at the 3-position. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 J2423605 | Certificate of Analysis | Jul 09, 2024 | P649870 |
| J2423611 | Certificate of Analysis | Jul 09, 2024 | P649870 |
| J2423614 | Certificate of Analysis | Jul 09, 2024 | P649870 |
| J2423615 | Certificate of Analysis | Jul 09, 2024 | P649870 |
| J2423617 | Certificate of Analysis | Jul 09, 2024 | P649870 |
| J2423619 | Certificate of Analysis | Jul 09, 2024 | P649870 |
| J2423621 | Certificate of Analysis | Jul 09, 2024 | P649870 |
| J2423624 | Certificate of Analysis | Jul 09, 2024 | P649870 |
| J2423625 | Certificate of Analysis | Jul 09, 2024 | P649870 |
| J2423626 | Certificate of Analysis | Jul 09, 2024 | P649870 |
| J2423628 | Certificate of Analysis | Jul 09, 2024 | P649870 |
| J2423630 | Certificate of Analysis | Jul 09, 2024 | P649870 |
| Solubility | DMSO : 250 mg/mL (800.46 mM; Need ultrasonic) |
|---|---|
| Sensitivity | Light sensitive |
| Molecular Weight | 312.320 g/mol |
| XLogP3 | 1.700 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 5 |
| Exact Mass | 312.111 Da |
| Monoisotopic Mass | 312.111 Da |
| Topological Polar Surface Area | 80.400 Ų |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 529.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
