Pitstop ® 1-25 - ≥99% , CAS No.1419321-16-6

CAS: 1419321-16-6 Cat. No.: P276479 Formula: C₁₉H₁₂KNO₅S Molecular Weight: 405.47 PubChem CID: 75593424

GRADE & PURITY ≥99%

Synonyms

3-Sulfo-N-(benzyl)-1,8-naphthalimidepotassiumsalt

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Overview

Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifications

Synonyms

3-Sulfo-N-(benzyl)-1,8-naphthalimidepotassiumsalt

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

Novel, selective clathrin inhibitor. Inhibits the clathrin terminal domain (IC 50 = 6.9 μM). No inhibition seen with dynamin and other key clathrin mediated endocytosis pathway proteins. Low cell permeability. Related products Pitstop ® 2 , Pi

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥99%

Names and Identifiers

Canonical Smiles

C1=CC=C(C=C1)CN2C(=O)C3=CC=CC4=CC(=CC(=C43)C2=O)S(=O)(=O)[O-].[K+]

IUPAC Name

potassium;2-benzyl-1,3-dioxobenzo[de]isoquinoline-5-sulfonate

InChIKey

XOIYIOVSMFKQQC-UHFFFAOYSA-M

INCHI

1S/C19H13NO5S.K/c21-18-15-8-4-7-13-9-14(26(23,24)25)10-16(17(13)15)19(22)20(18)11-12-5-2-1-3-6-12;/h1-10H,11H2,(H,23,24,25);/q;+1/p-1

Isomeric SMILES

C1=CC=C(C=C1)CN2C(=O)C3=CC=CC4=CC(=CC(=C43)C2=O)S(=O)(=O)[O-].[K+]

PubChem CID

75593424

Molecular Weight

405.47

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in DMSO

Frequently Asked Questions

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1419321-16-6, the molecular formula is C19H12KNO5S, and the molecular weight is 405.47 g/mol. InChIKey XOIYIOVSMFKQQC-UHFFFAOYSA-M.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.