PU 23 - ≥98%(HPLC) , CAS No.817635-93-1

CAS: 817635-93-1 Cat. No.: P287853 Molecular Weight: 425.52 PubChem CID: 4779049

GRADE & PURITY ≥98%(HPLC)

Synonyms

N-[[[4-[[(Phenylmethyl)amino]sulfonyl]phenyl]amino]thioxomethyl]benzamide

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Product introduction

Multidrug resistance protein (MRP) 4 inhibitor

Specifications

Synonyms

N-[[[4-[[(Phenylmethyl)amino]sulfonyl]phenyl]amino]thioxomethyl]benzamide

Specifications & Purity

≥98%(HPLC)

Biochemical and Physiological Mechanisms

Multidrug resistance protein (MRP) 4 inhibitor. Sensitizes MRP4-overexpressing cells to the anticancer agent6-Mercaptopurine(6-MP) (IC50values are 14.11 and 6.06 μM in the absence and presence of compound, respectively). Increases accumulation of 6-MP in

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥98%(HPLC)

Names and Identifiers

• Pubchem Sid: 504763128
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504763128
• Canonical Smiles: C1=CC=C(C=C1)CNS(=O)(=O)C2=CC=C(C=C2)NC(=S)NC(=O)C3=CC=CC=C3
• IUPAC Name: N-[[4-(benzylsulfamoyl)phenyl]carbamothioyl]benzamide
• InChIKey: RYIRRFWVFHEXTH-UHFFFAOYSA-N
• INCHI: 1S/C21H19N3O3S2/c25-20(17-9-5-2-6-10-17)24-21(28)23-18-11-13-19(14-12-18)29(26,27)22-15-16-7-3-1-4-8-16/h1-14,22H,15H2,(H2,23,24,25,28)
• PubChem CID: 4779049
• Molecular Weight: 425.52

Chemical and Physical Properties

• Solubility: Solvent:DMSO, Max Conc. mg/mL: 21.28, Max Conc. mM: 50