QS-21 - BioReagent, Lyophilized powder, Injection grade, ≥98%, Quillaja saponaria bark, used for QS‑21 has been validated in more than 120 clinical trials, with its safety and efficacy widely recognized. As a key component of the HA201a adjuvant system (C

CAS: 141256-04-4 Cat. No.: Q1527991 Formula: C92H148O46 Molecular Weight: 1990.15 EC Number: 814-254-2
AVAILABLE TO ORDER
GRADE & PURITY BioReagent ? BioReagent grade — tested suitable for life-science and molecular-biology use. Use for cell culture, assays, and biochemical work needing biological compatibility. Lyophilized powder ? Lyophilized (freeze-dried) powder — gently dried to preserve activity and aid storage. Use for sensitive biologics reconstituted before use. Injection grade ? Injection grade — high purity suitable for injectable/parenteral preparations. Use for formulations administered by injection where impurity limits are strict. ≥98% Quillaja saponaria bark
Synonyms
QS-21 Adjuvant,Stimulon
Storage
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
Application
990
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Size
Germany (EU)
USA*
Price
Qty
250μg
Q1527991-250μg
Made to order · 8–12 wks
€260.23
1mg
Q1527991-1mg
Made to order · 8–12 wks
€598.65
5mg
Q1527991-5mg
Made to order · 8–12 wks
€2,082.49
Enter a quantity for the sizes you want to add.
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Why this grade

BioReagent, Lyophilized powder, Injection grade, ≥98%, Quillaja saponaria bark BioReagent,Injection grade,Lyophilized powder for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

QS‑21 is a potent triterpenoid saponin immunostimulant, and one of the most clinically valuable naturally‑derived adjuvants following aluminium‑based adjuvants. As a natural vaccine adjuvant, QS‑21 can potently induce balanced Th1/Th2 immune responses, with particular potency in driving cellular immunity.

Name: QS‑21

Molecular Formula: C₉₂H₁₄₈O₄₆

Molecular Weight: 1990.15

CAS: 141256‑04‑4

Source: Purified from Quillaja saponaria bark

Grade: Injectable‑grade pharmaceutical excipient

Precautions

Protect from light and heat. Avoid contact with strong oxidizing substances. Do not subject to repeated freeze‑thaw cycles.

Specifications

Synonyms
QS-21 Adjuvant,Stimulon
Specifications & Purity
BioReagent, Lyophilized powder, Injection grade, ≥98%, Quillaja saponaria bark
Application
QS‑21 has been validated in more than 120 clinical trials, with its safety and efficacy widely recognized. As a key component of the HA201a adjuvant system (Cat. No.: H1526829) , this product can be utilized for the development of various vaccines. QS‑21
Stability And Storage
Store at-20℃ long term (36 months). Store in the dark.
Storage
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
BioReagent, Injection grade, Lyophilized powder
Purity
≥98%
Product Line
biological_products
Names and Identifiers
Isomeric SMILES
CC[C@H](C)[C@H](C[C@@H](CC(=O)O[C@@H](C[C@@H](CC(=O)O[C@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O[C@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)C)O[C@H]3[C@@H]([C@H]([C@@H](CO3)O)O[C@H]4[C@@H]([C@](CO4)(CO)O)O)O)O)O)OC(=O)[C@]56CCC(C[C@H]5C7=CC[C@@H]8[C@]9(CC[C@@H]([C@@]([C@@H]9CC[C@]8([C@@]7(C[C@H]6O)C)C)(C)C=O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)C(=O)O)O)O[C@H]1[C@@H]([C@H]([C@@H](CO1)O)O)O)O[C@H]1[C@@H]([C@H]([C@H]([C@H](O1)CO)O)O)O)C)(C)C)C)O)[C@@H](C)CC)O)O[C@H]1[C@@H]([C@H]([C@@H](O1)CO)O)O
Molecular Weight
1990.15

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SensitivityLight-sensitive
Documents & Articles
Solution Calculators
Reviews

Customer Reviews

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View BioReagent grade guide → View Lyophilized powder grade guide → View Injection grade grade guide →

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