(R)-PS210 - 10mM in DMSO , CAS No.1410101-89-1

CAS: 1410101-89-1 Cat. No.: P656290 Molecular Weight: 380.31

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

(R)-PS210, the R enantiomer of PS210 (compound 4h-eutomer), is a substrate-selective allosteric activator of PDK1 with an AC 50 value of 1.8 μM. (R)-PS210 targets to the PIF-binding pocket of PDK1. PIF: The protein kinase C-related kinase 2 (PRK2)-interacting fragment

In Vitro

(R)-PS210 displays an AC 50 value of 1.8 μM towards PDK1 in a Cell-Free Kinase Activity Assay. And the maximum activation of PDK1 compared to DMSO control of (R)-PS210 is 5.5 fold. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:AC50: 1.8 μM (PDK1)

Specifications

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

(R)-PS210, the R enantiomer of PS210 (compound 4h-eutomer), is a substrate-selective allosteric activator of PDK1 with an AC 50 value of 1.8 μM. (R)-PS210 targets to the PIF-binding pocket ofxa0PDK1. PIF: The protein kinase C-related kinase 2 (PRK2)-inter

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Names and Identifiers

• Molecular Weight: 380.31