Senexin A - ≥98%(HPLC) , CAS No.1780390-76-2

CAS: 1780390-76-2 Cat. No.: S288272 Formula: C₁₇H₁₄N₄.HCl Molecular Weight: 310.78 PubChem CID: 90488980

GRADE & PURITY ≥98%(HPLC)

Synonyms

4-[(2-Phenylethyl)amino]-6-quinazolinecarbonitrile hydrochloride

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Synonyms

4-[(2-Phenylethyl)amino]-6-quinazolinecarbonitrile hydrochloride

Specifications & Purity

≥98%(HPLC)

Biochemical and Physiological Mechanisms

Cyclin-dependent kinase 8 (cdk8) inhibitor (IC50= 280 nM). Also binds to cdk19 in an ATP-competitive manner. Inhibits p21-induced transcription. Reversesdoxorubicin-induced tumor-promoting paracrine activitiesin vivo.

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%(HPLC)

Names and Identifiers

• Canonical Smiles: C1=CC=C(C=C1)CCNC2=NC=NC3=C2C=C(C=C3)C#N.Cl
• IUPAC Name: 4-(2-phenylethylamino)quinazoline-6-carbonitrile;hydrochloride
• InChIKey: POENYXHGUHRXFR-UHFFFAOYSA-N
• INCHI: 1S/C17H14N4.ClH/c18-11-14-6-7-16-15(10-14)17(21-12-20-16)19-9-8-13-4-2-1-3-5-13;/h1-7,10,12H,8-9H2,(H,19,20,21);1H
• Isomeric SMILES: C1=CC=C(C=C1)CCNC2=NC=NC3=C2C=C(C=C3)C#N.Cl
• PubChem CID: 90488980
• Molecular Weight: 310.78

Chemical and Physical Properties

• Solubility: Solvent:DMSO, Max Conc. mg/mL: 31.08, Max Conc. mM: 100

Frequently Asked Questions

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What is the purity of this product, and how is it determined?

This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1780390-76-2, the molecular formula is C??H??N?.HCl, and the molecular weight is 310.78 g/mol. InChIKey POENYXHGUHRXFR-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.