Extremely potent KV1.3 channel blocker (Kd= 23 pM for mKV1.3 currents). Selective for KV1.3 over other mammalian potassium channels (IC50values are 23, 1800, 10500, 37000 and 39000 pM for mKV1.3, mKV1.1, hKV1.6, mKV1.4 and rKV1.2 respectively, and >100000
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