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Potassium voltage-gated channel subfamily H member 2 (KCNH2)
SHP389 - 10mM in DMSO , CAS No.2235394-90-6

SHP389 - 10mM in DMSO , CAS No.2235394-90-6

Name: SHP389 - 10mM in DMSO , CAS No.2235394-90-6
Brand: Aladdin Scientific
SKU: S656326
Availability: InStock

CAS: 2235394-90-6 Cat. No.: S656326 Molecular Weight: 484.98 PubChem CID: 124147932

COA

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SHP389 - 10mM in DMSO CAS No(2235394-90-6) by Aladdin Scientific

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AVAILABLE TO ORDER

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview Specifications Names and Identifiers Documentation Advanced Data Associated Targets(Human) Certificates（CoA,COO,BSE/TSE and Analysis Chart) Solution Calculators Reviews

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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

SHP389 is an allosteric SHP2 inhibitor, with an IC 50 of 36 nM for both SHP2 and p-ERK

In Vivo

SHP389 modulates MAPK signaling in vivo . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:IC50: 36 nM (SHP2 and p-ERK)

Specifications

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

SHP389 is an allosteric SHP2 inhibitor, with an IC 50 of 36 nM for both SHP2 and p-ERK.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

Isomeric SMILES	C[C@H]1[C@H](C2(CCN(CC2)C3=NC4=NNC(=C4C(=O)N3C)C5=C(C(=NC=C5)NC6CC6)Cl)CO1)N
PubChem CID	124147932
Molecular Weight	484.98

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)

PTPN11 Tchem Tyrosine-protein phosphatase non-receptor type 11 (2 Activities)

Discover Target: PTPN11

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Solution Calculators

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Reviews

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